重组Anti-SYN4抗体[EPR8707] (ab133767)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR8707] to SYN4
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
Related conjugates and formulations
概述
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产品名称
Anti-SYN4抗体[EPR8707]
参阅全部 SYN4 一抗 -
描述
兔单克隆抗体[EPR8707] to SYN4 -
宿主
Rabbit -
经测试应用
适用于: WBmore details
不适用于: IHC-P or IP -
种属反应性
与反应: Mouse, Rat, Human -
免疫原
Synthetic peptide within Human SYN4 aa 1-100. The exact sequence is proprietary.
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阳性对照
- Mouse brain, Rat brain and Human fetal brain lysates.
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常规说明
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
解离常数(KD)
KD = 1.37 x 10 -10 M Learn more about KD -
存储溶液
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading...
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纯度
Tissue culture supernatant -
克隆
单克隆 -
克隆编号
EPR8707 -
同种型
IgG -
研究领域
相关产品
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Alternative Versions
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab133767于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/1000 - 1/10000. Detects a band of approximately 50 kDa (predicted molecular weight: 58 kDa).
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说明 |
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WB
1/1000 - 1/10000. Detects a band of approximately 50 kDa (predicted molecular weight: 58 kDa). |
靶标
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功能
Adapter protein that binds to and probably organizes the subcellular localization of a variety of proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex (By similarity). May participate in regulating the subcellular location of diacylglycerol kinase-zeta to ensure that diacylglycerol is rapidly inactivated following receptor activation. -
组织特异性
Brain specific. In CNS, it is expressed in the perikaryon and proximal portion of the neuronal processes. Strong expression in the hippocampus, neuron-rich dendate granule cells, and pyramidal cell layers. Highly expressed in neurons of the cerebral cortex. Also expressed in the cerebellar cortex, deep cerebellar nuclei, thalamus, and basal ganglia. No expression in muscle cells. -
序列相似性
Belongs to the syntrophin family.
Contains 1 PDZ (DHR) domain.
Contains 1 PH domain. -
结构域
The PDZ domain binds to the last three or four amino acids of DGKZ. The association with dystrophin or related proteins probably leaves the PDZ domain available to recruit proteins to the membrane. -
细胞定位
Cytoplasm > cytoskeleton. Nucleus. Mainly cytoplasmic and weakly nuclear. - Information by UniProt
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数据库链接
- Entrez Gene: 54212 Human
- Entrez Gene: 71096 Mouse
- Entrez Gene: 500394 Rat
- Omim: 608714 Human
- SwissProt: Q9NSN8 Human
- SwissProt: Q925E1 Mouse
- Unigene: 584914 Human
- Unigene: 388998 Mouse
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别名
- G1SYN antibody
- Gamma 1 syntrophin antibody
- Gamma-1-syntrophin antibody
see all
图片
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All lanes : Anti-SYN4 antibody [EPR8707] (ab133767) at 1/1000 dilution
Lane 1 : Mouse brain lysate
Lane 2 : Rat brain lysate
Lane 3 : Human fetal brain lysate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : HRP labelled Goat anti Rabbit IgG at 1/2000 dilution
Predicted band size: 58 kDa
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab133767 尚未被引用在任何文献中。