Anti-SYN2抗体(ab13258)
Key features and details
- Rabbit polyclonal to SYN2
- Suitable for: IP, ICC/IF, WB
- Reacts with: Mouse, Rat
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术，可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-SYN2抗体
参阅全部 SYN2 一抗 -
描述
兔多克隆抗体to SYN2 -
宿主
Rabbit -
经测试应用
适用于: IP, ICC/IF, WBmore details -
种属反应性
与反应: Mouse, Rat
预测可用于: Human
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免疫原
Synthetic peptide corresponding to Rat SYN2 aa 50-150 conjugated to keyhole limpet haemocyanin.
Database link: Q63537 -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
Preservative: 0.09% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine) -
Concentration information loading... -
纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab13258于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IP |
Use at an assay dependent concentration.
|
|
| ICC/IF |
Use at an assay dependent concentration. PubMed: 19714568
|
|
| WB | (1) |
Use at an assay dependent concentration.
|
| 说明 |
|---|
|
IP
Use at an assay dependent concentration. |
|
ICC/IF
Use at an assay dependent concentration. PubMed: 19714568 |
|
WB
Use at an assay dependent concentration. |
靶标
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功能
Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. May play a role in noradrenaline secretion by sympathetic neurons. -
组织特异性
Central and peripheral nervous systems. -
序列相似性
Belongs to the synapsin family. -
结构域
The A region binds phospholipids with a preference for negatively charged species. -
翻译后修饰
Phosphorylation at Ser-10 dissociates synapsins from synaptic vesicles. Phosphorylation at Ser-425 by MAPK1/ERK2 and/or MAPK3/ERK1 may play a role in noradrenaline secretion by sympathetic neurons. -
细胞定位
Cell junction, synapse. - Information by UniProt
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数据库链接
- Entrez Gene: 6854 Human
- Entrez Gene: 20965 Mouse
- Entrez Gene: 29179 Rat
- Omim: 600755 Human
- SwissProt: Q92777 Human
- SwissProt: Q64332 Mouse
- SwissProt: Q63537 Rat
- Unigene: 445503 Human
see all -
别名
- SYN 2 antibody
- SYN II antibody
- SYN IIa antibody
see all
数据表及文件
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SDS download
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Datasheet download
文献 (11)
ab13258 被引用在 11 文献中.
- Schwark R et al. Synapsin II Directly Suppresses Epileptic Seizures In Vivo. Brain Sci 12:N/A (2022). PubMed: 35326282
- Dreumont N et al. Glucocorticoid Receptor Activation Restores Learning Memory by Modulating Hippocampal Plasticity in a Mouse Model of Brain Vitamin B12 Deficiency. Mol Neurobiol 58:1024-1035 (2021). PubMed: 33078371
- Liu SB et al. Cyclic AMP-dependent positive feedback signaling pathways in the cortex contributes to visceral pain. J Neurochem 153:252-263 (2020). PubMed: 31665810
- Jadhav VS et al. Trem2 Y38C mutation and loss of Trem2 impairs neuronal synapses in adult mice. Mol Neurodegener 15:62 (2020). PubMed: 33115519
- Plumel M et al. Circadian Analysis of the Mouse Cerebellum Proteome. Int J Mol Sci 20:N/A (2019). PubMed: 30991638