Anti-SUV3L1抗体(ab127909)
Key features and details
- Rabbit polyclonal to SUV3L1
- Suitable for: WB, ICC/IF
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-SUV3L1抗体
参阅全部 SUV3L1 一抗 -
描述
兔多克隆抗体to SUV3L1 -
宿主
Rabbit -
经测试应用
适用于: WB, ICC/IFmore details -
种属反应性
与反应: Human -
免疫原
Recombinant fragment, corresponding to a region within C terminal amino acids 545-739 of Human SUV3L1 (Q8IYB8).
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阳性对照
- PC3 whole cell lysate; HeLa cells.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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纯度
Immunogen affinity purified -
纯化说明
ab127909 is purified by antigen-affinity chromatography. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab127909于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/500 - 1/3000. Predicted molecular weight: 88 kDa.
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ICC/IF |
1/100 - 1/1000.
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说明 |
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WB
1/500 - 1/3000. Predicted molecular weight: 88 kDa. |
ICC/IF
1/100 - 1/1000. |
靶标
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功能
Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA. -
组织特异性
Broadly expressed. -
序列相似性
Belongs to the helicase family.
Contains 1 helicase ATP-binding domain.
Contains 1 helicase C-terminal domain. -
细胞定位
Nucleus. Mitochondrion matrix. Mitochondrion matrix > mitochondrion nucleoid. - Information by UniProt
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数据库链接
- Entrez Gene: 6832 Human
- Omim: 605122 Human
- SwissProt: Q8IYB8 Human
- Unigene: 106469 Human
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别名
- 6330443E10Rik antibody
- ATP dependent RNA helicase SUPV3L1, mitochondrial antibody
- ATP-dependent RNA helicase SUPV3L1 antibody
see all
图片
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Anti-SUV3L1 antibody (ab127909) at 1/1000 dilution + PC3 whole cell lysate at 30 µg
Developed using the ECL technique.
Predicted band size: 88 kDa
7.5% SDS PAGE -
ab127909 at 1/500 dilution staining SUV3L1 in methanol-fixed HeLa cells by confocal Immunofluorescence. Alpha-tubulin filaments are stained in red.
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab127909 尚未被引用在任何文献中。