Anti-Sumo 3抗体(ab5317)
Key features and details
- Rabbit polyclonal to Sumo 3
- Suitable for: WB
- Reacts with: Arabidopsis thaliana
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术，可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-Sumo 3抗体
参阅全部 Sumo 3 一抗 -
描述
兔多克隆抗体to Sumo 3 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Arabidopsis thaliana -
免疫原
Recombinant full length protein corresponding to Arabidopsis thaliana Sumo 3 aa 1 to the C-terminus.
Database link: Q9FLP5 -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Concentration information loading... -
纯度
Whole antiserum -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB | (1) |
1/1000. Predicted molecular weight: 12 kDa.
|
| 说明 |
|---|
|
WB
1/1000. Predicted molecular weight: 12 kDa. |
靶标
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功能
Ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. -
组织特异性
Expressed predominantly in liver. -
序列相似性
Belongs to the ubiquitin family. SUMO subfamily.
Contains 1 ubiquitin-like domain. -
翻译后修饰
Polymeric chains can be formed through Lys-11 cross-linking.
Cleavage of precursor form by SENP1, SENP2 or SENP5 is necessary for function. -
细胞定位
Cytoplasm. - Information by UniProt
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别名
- Small ubiquitin like modifier 3 antibody
- Small ubiquitin related modifier 3 antibody
- Small ubiquitin-related modifier 3 antibody
see all
图片
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Western blot - Anti-Sumo 3 antibody (ab5317)
Western blots of SUMO1 and SUMO3 antibody on arabidopsis extracts heat treated for the indicated times by moving them from 24 to 37 degrees C. The panel on the left was using ab5316, the panel on the right was using ab5317 - both antibodies were used at a dilution of 1/1000.
Western blots of SUMO1 and SUMO3 antibody on arabidopsis extracts heat treated for the indicated times by moving them from 24 to 37 degrees C. The panel on the left was using ab5316, the panel on the right was using ab5317 - both antibodies were used at a dilution of 1/1000.
数据表及文件
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Datasheet download
文献 (4)
ab5317 被引用在 4 文献中.
- Dvořák Tomaštíková E et al. SMC5/6 complex-mediated SUMOylation stimulates DNA-protein cross-link repair in Arabidopsis. Plant Cell 35:1532-1547 (2023). PubMed: 36705512
- Cheng X et al. Sumoylation of Turnip mosaic virus RNA Polymerase Promotes Viral Infection by Counteracting the Host NPR1-Mediated Immune Response. Plant Cell 29:508-525 (2017). PubMed: 28223439
- Budhiraja R et al. Substrates related to chromatin and to RNA-dependent processes are modified by Arabidopsis SUMO isoforms that differ in a conserved residue with influence on desumoylation. Plant Physiol 149:1529-40 (2009). WB ; Arabidopsis thaliana . PubMed: 19151129
- Kurepa J et al. The small ubiquitin-like modifier (SUMO) protein modification system in Arabidopsis. Accumulation of SUMO1 and -2 conjugates is increased by stress. J Biol Chem 278:6862-72 (2003). PubMed: 12482876
