抗化脓性链球菌Group A Carbohydrate抗体(ab9191)
Key features and details
- Goat polyclonal to Streptococcus pyogenes Group A Carbohydrate
- Suitable for: Dot blot, ELISA, ICC/IF, IHC-Fr, IP, WB, IHC-P
- Reacts with: Streptococcus pyogenes
- Isotype: IgG
概述
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产品名称
抗化脓性链球菌Group A Carbohydrate抗体 -
描述
山羊多克隆抗体to化脓性链球菌Group A Carbohydrate -
宿主
Goat -
特异性
Streptococcus Pyogenes Group A -
经测试应用
适用于: Dot blot, ELISA, ICC/IF, IHC-Fr, IP, WB, IHC-Pmore details -
种属反应性
与反应: Streptococcus pyogenes -
免疫原
Tissue, cells or virus corresponding to Streptococcus pyogenes Streptococcus pyogenes Group A Carbohydrate. Killed Streptococcus pyogenes vaccine Strain J17A4.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.20
Constituent: 0.0268% PBS -
Concentration information loading... -
纯度
Immunogen affinity purified -
纯化说明
Serum was collected and antibody to the Group A carbohydrate was immunoaffinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
| 应用 | Ab评论 | 说明 |
|---|---|---|
| Dot blot |
Use at an assay dependent concentration.
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| ELISA |
Use at an assay dependent concentration.
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| ICC/IF |
Use at an assay dependent concentration.
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| IHC-Fr |
Use at an assay dependent concentration.
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| IP |
Use at an assay dependent concentration.
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| WB |
Use at an assay dependent concentration.
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| IHC-P |
Use at an assay dependent concentration. PubMed: 29416987
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| 说明 |
|---|
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Dot blot
Use at an assay dependent concentration. |
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ELISA
Use at an assay dependent concentration. |
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ICC/IF
Use at an assay dependent concentration. |
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IHC-Fr
Use at an assay dependent concentration. |
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IP
Use at an assay dependent concentration. |
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WB
Use at an assay dependent concentration. |
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IHC-P
Use at an assay dependent concentration. PubMed: 29416987 |
靶标
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相关性
Streptococcus pyogenes (Group A streptococcus) is a Gram-positive, nonmotile, nonsporeforming coccus that occurs in chains or in pairs of cells. Individual cells are round-to-ovoid cocci, 0.6-1.0 micrometer in diameter. Streptococci divide in one plane and thus occur in pairs or (especially in liquid media or clinical material) in chains of varying lengths. The metabolism of S. pyogenes is fermentative; the organism is a catalase-negative aerotolerant anaerobe (facultative anaerobe), and requires enriched medium containing blood in order to grow. Group A streptococci typically have a capsule composed of hyaluronic acid and exhibit beta (clear) hemolysis on blood agar.
实验方案
数据表及文件
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Datasheet download
文献 (10)
ab9191 被引用在 10 文献中.
- Rush JS et al. PplD is a de-N-acetylase of the cell wall linkage unit of streptococcal rhamnopolysaccharides. Nat Commun 13:590 (2022). PubMed: 35105886
- Hurst JR et al. The Streptococcus pyogenes hyaluronic acid capsule promotes experimental nasal and skin infection by preventing neutrophil-mediated clearance. PLoS Pathog 18:e1011013 (2022). PubMed: 36449535
- Toh H et al. Group A Streptococcus modulates RAB1- and PIK3C3 complex-dependent autophagy. Autophagy 16:334-346 (2020). PubMed: 31177902
- Volzke J et al. Inflammatory Joint Disease Is a Risk Factor for Streptococcal Sepsis and Septic Arthritis in Mice. Front Immunol 11:579475 (2020). PubMed: 33117382
- Siggins MK et al. Extracellular bacterial lymphatic metastasis drives Streptococcus pyogenes systemic infection. Nat Commun 11:4697 (2020). PubMed: 32943639
- Tanaka M et al. Group A Streptococcus establishes pharynx infection by degrading the deoxyribonucleic acid of neutrophil extracellular traps. Sci Rep 10:3251 (2020). PubMed: 32094510
- Toh H et al. Group A Streptococcus NAD-Glycohydrolase Inhibits Caveolin 1-Mediated Internalization Into Human Epithelial Cells. Front Cell Infect Microbiol 9:398 (2019). PubMed: 31850237
- Sumitomo T et al. Streptococcal Cysteine Protease-Mediated Cleavage of Desmogleins Is Involved in the Pathogenesis of Cutaneous Infection. Front Cell Infect Microbiol 8:10 (2018). IHC-P . PubMed: 29416987
- Hertzog BB et al. A Sub-population of Group A Streptococcus Elicits a Population-wide Production of Bacteriocins to Establish Dominance in the Host. Cell Host Microbe 23:312-323.e6 (2018). PubMed: 29544095
- Rush JS et al. The molecular mechanism of N-acetylglucosamine side-chain attachment to the Lancefield group A carbohydrate in Streptococcus pyogenes. J Biol Chem 292:19441-19457 (2017). PubMed: 29021255
