Anti-STOX1抗体(ab122420)
Key features and details
- Rabbit polyclonal to STOX1
- Suitable for: IHC-P, ICC/IF
- Reacts with: Human
- Isotype: IgG
概述
-
产品名称
Anti-STOX1抗体
参阅全部 STOX1 一抗 -
描述
兔多克隆抗体to STOX1 -
宿主
Rabbit -
经测试应用
适用于: IHC-P, ICC/IFmore details -
种属反应性
与反应: Human -
免疫原
antigen sequence: SEFQPGSIRL EKHPKLPATQ PIPRIKSPNE MVGQKPLGEI TTVLGSHLIY KKRISNPFQG LSHRGSTISK GHKIQKTSDL KPSQTGPKEK, corresponding to amino acids 440-529 of Human STOX1.
-
阳性对照
- Human adrenal gland tissue, U-251 MG cells
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine) -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab122420于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P |
1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
|
|
| ICC/IF |
Use a concentration of 0.25 - 2 µg/ml.
|
| 说明 |
|---|
|
IHC-P
1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
|
ICC/IF
Use a concentration of 0.25 - 2 µg/ml. |
靶标
-
疾病相关
Defects in STOX1 are the cause of pre-eclampsia/eclampsia 4 (PEE4) [MIM:609404]; also known as gestational proteinuric hypertension. Preeclampsia is a pregnancy-associated disease with maternal symptoms but placental origin. Unlike most other human disorders, it impacts 2 individuals, the mother and her child, both of whom can be severely affected. The pathological mechanism of PEE4 involves the loss of function of STOX1 in the placenta. -
细胞定位
Nucleus; Nucleus > nucleolus and Cytoplasm. Nucleus. Either found in the cytoplasm or in the nucleus. Nuclear expression of isoform A seems to be restricted to polyploid trophoblast cells. - Information by UniProt
-
数据库链接
- Entrez Gene: 219736 Human
- Omim: 609397 Human
- SwissProt: Q6ZVD7 Human
- Unigene: 37636 Human
-
别名
- C10orf24 antibody
- chromosome 10 open reading frame 241 antibody
- PEE4 antibody
see all
图片
-
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-STOX1 antibody (ab122420)ab122420 at 1/50 dilution staining STOX1 in Paraffin-embedded Human adrenal gland tissue by Immunohistochemistry.
-
Immunocytochemistry/ Immunofluorescence - Anti-STOX1 antibody (ab122420)Immunofluorescent staining of Human cell line U-251 MG using ab122420 at a concentration of 4 µg/ml. ab122420 staining is shown in green.
实验方案
数据表及文件
-
SDS download
-
Datasheet download
文献 (0)
ab122420 尚未被引用在任何文献中。