Anti-Spermine 抗体

补充信息

This supplementary information is collated from multiple sources and compiled automatically.

Biological function summary

Spermine modulates various cellular processes. It is involved in cell growth and differentiation and it stabilizes cell membranes. By binding to DNA spermine helps preserve its structure during stress. Additionally spermine acts as an antioxidant reducing oxidative damage in the cells. Polyamines such as spermine often function independently rather than as part of a complex. The regulation of their synthesis and uptake is controlled by enzymes including ornithine decarboxylase which is an important player in polyamine biosynthesis.

Pathways

Spermine is central in the polyamine biosynthesis pathway which is vital for cellular proliferation. It regulates pathways involved in the synthesis and breakdown of proteins. The action of spermine interlinks with the metabolism of amino acids like ornithine and methionine influencing the biogenic amines pathway. Spermine's metabolic pathway intersects with proteins such as S-adenosylmethionine decarboxylase and spermidine synthase which closely control its levels in the cell.