Anti-SPANX抗体(ab119280)
Key features and details
- Rabbit polyclonal to SPANX
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-SPANX抗体
参阅全部 SPANX 一抗 -
描述
兔多克隆抗体to SPANX -
宿主
Rabbit -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Chimpanzee, Gorilla
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免疫原
Synthetic peptide:
GDSDPQPAPKKMKTSES
conjugated to KLH, corresponding to amino acids 31-47 of Human SPANX. -
阳性对照
- Human testis tissue.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 0.88% Sodium chloride, 0.424% Potassium phosphate -
Concentration information loading... -
纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab119280于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P |
Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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| 说明 |
|---|
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IHC-P
Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
靶标
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组织特异性
Detected in testis, melanoma and bladder carcinoma. -
序列相似性
Belongs to the SPAN-X family. -
发展阶段
Detected in round and elongating spermatids. -
细胞定位
Cytoplasm. Nucleus. Associated with nuclear craters. - Information by UniProt
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数据库链接
- Entrez Gene: 64663 Human
- Omim: 300330 Human
- SwissProt: A0FGV1 Human
- SwissProt: A0FGV4 Human
- SwissProt: A0FGW6 Human
- SwissProt: A0FGX0 Human
- SwissProt: Q32WM2 Human
- SwissProt: Q9NY87 Human
see all -
别名
- Cancer-testis-associated protein CTp11 antibody
- Cancer/testis antigen 11.3 antibody
- Cancer/testis-associated protein CTp11 antibody
see all
图片
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SPANX antibody (ab119280)ab119280, at 5 ug/ml, staining SPANX in formalin-fixed, paraffin-embedded Human testis tissue, followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.
数据表及文件
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SDS download
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Datasheet download
文献 (3)
ab119280 被引用在 3 文献中.
- Urizar-Arenaza I et al. The multifunctional role of SPANX-A/D protein subfamily in the promotion of pro-tumoural processes in human melanoma. Sci Rep 11:3583 (2021). PubMed: 33574425
- Urizar-Arenaza I et al. SPANX-A/D protein subfamily plays a key role in nuclear organisation, metabolism and flagellar motility of human spermatozoa. Sci Rep 10:5625 (2020). PubMed: 32221341
- Lazar I et al. SPANX Control of Lamin A/C Modulates Nuclear Architecture and Promotes Melanoma Growth. Mol Cancer Res 18:1560-1573 (2020). PubMed: 32571981