Anti-SOX22抗体[86C2a] (ab54371)
![Western blot - Anti-SOX22 antibody [86C2a] (ab54371)](https://www.abcam.cn/ps/products/54/ab54371/Images/ab54371-67214-anti-sox22-antibody-86c2a-western-blot.gif "Western blot - Anti-SOX22 antibody [86C2a] (ab54371)")
Key features and details
- Mouse monoclonal [86C2a] to SOX22
- Suitable for: WB
- Reacts with: Recombinant fragment
- Isotype: IgG2a
概述
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产品名称
Anti-SOX22抗体[86C2a] -
描述
小鼠单克隆抗体[86C2a] to SOX22 -
宿主
Mouse -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Recombinant fragment -
免疫原
SOX22 recombinant fragment (Human)
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
存储溶液
pH: 7.40
Preservative: 0.05% Sodium azide
Constituents: 1% BSA, 0.03% Potassium phosphate, 0.812% Sodium chloride, 0.1312% Sodium phosphate, 0.0225% Potassium chloride, PBS -
Concentration information loading... -
纯度
Protein G purified -
纯化说明
ab54371 was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum and filtered through a 0.22µm membrane. -
克隆
单克隆 -
克隆编号
86C2a -
同种型
IgG2a -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab54371于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use at an assay dependent concentration. Detects a band of approximately 30 kDa (predicted molecular weight: 34 kDa).
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| 说明 |
|---|
|
WB
Use at an assay dependent concentration. Detects a band of approximately 30 kDa (predicted molecular weight: 34 kDa). |
靶标
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功能
Binds to the sequence 5'-AACAAT-3'. -
组织特异性
Expressed most abundantly in the CNS. Also expressed in fetal brain and kidney and adult heart, pancreas, testis and ovary. Other tissues were only weakly positive. -
序列相似性
Contains 1 HMG box DNA-binding domain. -
细胞定位
Nucleus. - Information by UniProt
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别名
- Homo sapiens SRY (sex determining region Y) box 12 antibody
- Protein SOX-22 antibody
- SOX 12 antibody
see all
图片
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Western blot - Anti-SOX22 antibody [86C2a] (ab54371)Anti-SOX22 antibody [86C2a] (ab54371) + immunised recombinant protein
Predicted band size: 34 kDa
Observed band size: 30 kDa why is the actual band size different from the predicted?
数据表及文件
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Datasheet download
文献 (5)
ab54371 被引用在 5 文献中.
- Zhai D et al. LncRNA LGALS8-AS1 Promotes Breast Cancer Metastasis Through miR-125b-5p/SOX12 Feedback Regulatory Network. Front Oncol 11:711684 (2021). PubMed: 34745940
- Shen Y et al. LncRNA MNX1-AS1 promotes ovarian cancer process via targeting the miR-744-5p/SOX12 axis. J Ovarian Res 14:161 (2021). PubMed: 34789303
- Wei L et al. TMPO-AS1, a Novel E2F1-Regulated lncRNA, Contributes to the Proliferation of Lung Adenocarcinoma Cells via Modulating miR-326/SOX12 Axis. Cancer Manag Res 12:12403-12414 (2020). PubMed: 33293866
- Du F et al. Sex determining region Y-box 12 (SOX12) promotes gastric cancer metastasis by upregulating MMP7 and IGF1. Cancer Lett 452:103-118 (2019). PubMed: 30922917
- Zhang W et al. MicroRNA-744 inhibits migration and invasion of hepatocellular carcinoma cells by targeting SOX12. Oncol Rep 40:3585-3592 (2018). PubMed: 30542724
