Anti-SLUG抗体[mAbcam51772] (ab51772)
Key features and details
- Mouse monoclonal [mAbcam51772] to SLUG
- Suitable for: WB
- Reacts with: Mouse, Human
- Isotype: IgG1
概述
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产品名称
Anti-SLUG抗体[mAbcam51772]
参阅全部 SLUG 一抗 -
描述
小鼠单克隆抗体[mAbcam51772] to SLUG -
宿主
Mouse -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Mouse, Human
预测可用于: Chicken, Cow, Pig, Xenopus laevis -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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阳性对照
- Mouse Skin Tissue Lysate
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常规说明
This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact orders@abcam.com.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: PBS, 6.97% L-Arginine -
Concentration information loading...
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纯度
Protein G purified -
克隆
单克隆 -
克隆编号
mAbcam51772 -
骨髓瘤
Sp2/0 -
同种型
IgG1 -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab51772于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB | (4) |
Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 30 kDa.
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说明 |
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WB
Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 30 kDa. |
靶标
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功能
Transcriptional repressor. Involved in the generation and migration of neural crest cells. -
组织特异性
Expressed in placenta and adult heart, pancreas, liver, kidney and skeletal muscle. -
疾病相关
Defects in SNAI2 are the cause of Waardenburg syndrome type 2D (WS2D) [MIM:608890]. WS2 is a genetically heterogeneous, autosomal dominant disorder characterized by sensorineural deafness, pigmentary disturbances, and absence of dystopia canthorum. The frequency of deafness is higher in WS2 than in WS1. -
序列相似性
Belongs to the snail C2H2-type zinc-finger protein family.
Contains 5 C2H2-type zinc fingers. -
细胞定位
Nucleus. - Information by UniProt
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数据库链接
- Entrez Gene: 432368 Chicken
- Entrez Gene: 6591 Human
- Entrez Gene: 20583 Mouse
- Entrez Gene: 379440 Xenopus laevis
- Omim: 602150 Human
- SwissProt: Q3MHQ4 Cow
- SwissProt: O43623 Human
- SwissProt: P97469 Mouse
see all -
别名
- MGC10182 antibody
- Neural crest transcription factor Slug antibody
- Protein snail homolog 2 antibody
see all
图片
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All lanes : Anti-SLUG antibody [mAbcam51772] (ab51772)
Lane 1 : Untransfected MCF7 cells
Lane 2 : MCF7 cells transfected with SLUG
Lane 3 : MCF7 cells transfected with Snail
Predicted band size: 30 kDa
Observed band size: 30 kDa -
Anti-SLUG antibody [mAbcam51772] (ab51772) at 5 µg/ml +
Mouse skin tissue lysate - total protein (ab4025) at 10 µg
Secondary
Goat polyclonal to Mouse IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
Performed under reducing conditions.
Predicted band size: 30 kDa
Observed band size: 30 kDa
Additional bands at: 34 kDa, 60 kDa. We are unsure as to the identity of these extra bands.
Exposure time: 10 minutes -
All lanes : Anti-SLUG antibody [mAbcam51772] (ab51772) at 1 µg/ml
Lane 1 : Skin tissue lysate from Slug heterozygous mouse
Lane 2 : Skin tissue lysate from Slug knockout mouse
Performed under reducing conditions.
Predicted band size: 30 kDa
数据表及文件
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Datasheet download
文献 (44)
ab51772 被引用在 44 文献中.
- Jin Y et al. Up-regulation of collagen type V alpha 2 (COL5A2) promotes malignant phenotypes in gastric cancer cell via inducing epithelial-mesenchymal transition (EMT). Open Med (Wars) 18:20220593 (2023). PubMed: 36712590
- Gao N et al. Long non-coding RNA LINC00707, a prognostic marker, regulates cell proliferation, apoptosis, and EMT in esophageal squamous cell carcinoma. Am J Transl Res 15:2426-2442 (2023). PubMed: 37193148
- Liang X et al. Inhibition of lncRNA RET enhances radio-sensitivity of tumor cells via miR-3179/Slug/PTEN axis. Toxicol Res (Camb) 11:348-360 (2022). PubMed: 35510230
- Gao Y et al. SENP1 promotes triple-negative breast cancer invasion and metastasis via enhancing CSN5 transcription mediated by GATA1 deSUMOylation. Int J Biol Sci 18:2186-2201 (2022). PubMed: 35342335
- Chen X et al. Identification of hub genes predicting the development of prostate cancer from benign prostate hyperplasia and analyzing their clinical value in prostate cancer by bioinformatic analysis. Discov Oncol 13:54 (2022). PubMed: 35768705