AB239511

Anti-Ferroportin抗体[C8]

Name: SLC40A1抗体[C8] (ab239511)| Abcam中文官网
Brand: Abcam Limited
SKU: AB239511
Price: 4864 CNY
Availability: InStock

Anti-Ferroportin antibody [C8]

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(14 Publications)

Mouse Monoclonal SLC40A1 antibody. Suitable for WB and reacts with Human samples. Cited in 14 publications. Immunogen corresponding to Recombinant Fragment Protein within Human Ferroportin aa 100-350.

查看别名

FPN, FPN1, IREG1, SLC11A3, MSTP079, SLC40A1, Ferroportin, Ferroportin-1, Iron-regulated transporter 1, Solute carrier family 40 member 1

1 Images

Supplier Data

Western blot - Anti-Ferroportin antibody [C8] (AB239511)

All lanes:

Western blot - Anti-Ferroportin antibody [C8] (ab239511) at 5 µg/mL

All lanes:

Recombinant human SLC40A1 protein

Predicted band size: 63 kDa

false

关键信息

宿主种属

Mouse

克隆

Monoclonal

克隆号

亚型

IgG2b

轻链类型

kappa

不含载体蛋白

反应种属

Human

应用

applications

免疫原

Recombinant Fragment Protein within Human Ferroportin aa 100-350. The exact immunogen used to generate this antibody is proprietary information.

Q9NP59

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.5-5 µg/mL", "WB-species-notes": "<p></p>" }, "Rat": { "WB-species-checked": "notRecommended", "WB-species-dilution-info": "0.5-5 µg/mL", "WB-species-notes": "<p></p>" } } }

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性能和储存信息

形式

Liquid

纯化工艺

Affinity purification Protein A/G

纯化说明

Purified from TCS.

存储溶液

pH: 7.4 Preservative: 0.011% Proclin 300 Constituents: PBS, 55.77% Glycerol (glycerin, glycerine)

运输条件

Blue Ice

分装信息

Upon delivery aliquot

储存信息

Avoid freeze / thaw cycle

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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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靶点信息

Transports Fe(2+) from the inside of a cell to the outside of the cell, playing a key role for maintaining systemic iron homeostasis (PubMed : 15692071, PubMed : 22178646, PubMed : 22682227, PubMed : 24304836, PubMed : 29237594, PubMed : 29599243, PubMed : 30247984). Transports iron from intestinal, splenic, hepatic cells, macrophages and erythrocytes into the blood to provide iron to other tissues (By similarity). Controls therefore dietary iron uptake, iron recycling by macrophages and erythrocytes, and release of iron stores in hepatocytes (By similarity). When iron is in excess in serum, circulating HAMP/hepcidin levels increase resulting in a degradation of SLC40A1, thus limiting the iron efflux to plasma (PubMed : 22682227, PubMed : 29237594, PubMed : 32814342).

See full target information Ferroportin

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文献 (14)

Recent publications for all applications. Explore the full list and refine your search

American journal of cancer research 15:3434-3448 PubMed40948531

2025

Differentiating early-stage nasopharyngeal carcinoma from adenoidal hypertrophy via SLC40A1 expression and developing a prognostic model for disease progression.

Applications

Unspecified application

Species

Unspecified reactive species

Hongwei Wang,Suqing Qi,Chaobing Liu,Zhenhua Qiao,Chao Zhang

World journal of gastrointestinal oncology 17:104522 PubMed40487942

2025

Simvastatin inhibits proliferation and migration, promotes oxidative stress and ferroptosis in colon cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Ying Liu,Hao Ge,Zhi-Min Fan,Ting Lu,Lei He,Meng Li,Hao-Ran Zhao,Qiang Leng

Journal of molecular neuroscience : MN 75:63 PubMed40317390

2025

Electroacupuncture Inhibits Ferroptosis by Modulating Iron Metabolism and Oxidative Stress to Alleviate Cerebral Ischemia-Reperfusion Injury.

Applications

Unspecified application

Species

Unspecified reactive species

Yaoyao Liu,Qi Wang,Ziwen Hou,Ying Gao,Peng Li

Molecular medicine reports 31: PubMed40183404

2025

α‑ketoglutarate protects against septic cardiomyopathy by improving mitochondrial mitophagy and fission.

Applications

Unspecified application

Species

Unspecified reactive species

Wei Wu,Qiong Ma,Bo-Tao Li,Shuang Shi,Gong-Chang Guan,Jun-Kui Wang,Bao-Yao Xue,Zhong-Wei Liu

Frontiers in pharmacology 15:1503064 PubMed39619616

2024

Tetramethylpyrazine inhibits ferroptosis in spinal cord injury by regulating iron metabolism through the NRF2/ARE pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Jingwei Tao,Jingya Zhou,Hanjie Zhu,Lin Xu,Jizhou Yang,Xiaohong Mu,Xiao Fan

Heliyon 10:e33675 PubMed39071725

2024

Acupuncture improve proteinuria in diabetic kidney disease rats by inhibiting ferroptosis and epithelial-mesenchymal transition.

Applications

Unspecified application

Species

Unspecified reactive species

J I Yue,Z H A N G Xin-Yuan,X I A O Yun-Ming,Z H U A N G Zi-Hao,Y A N G Xiao-Hui,L I Xin-Ju

Environmental science and pollution research international 30:111051-111061 PubMed37801247

2023

PM 2.5 juvenile exposure-induced spermatogenesis dysfunction by triggering testes ferroptosis and antioxidative vitamins intervention in adult male rats.

Applications

Unspecified application

Species

Unspecified reactive species

Xiang Liu,Yaya Ai,Mingchen Xiao,Cao Wang,Zhen Shu,Jia Yin,Yu Chu,Qing Xiao,Bin Liu

Redox biology 62:102708 PubMed37116254

2023

17β-oestradiol inhibits ferroptosis in the hippocampus by upregulating DHODH and further improves memory decline after ovariectomy.

Applications

Unspecified application

Species

Unspecified reactive species

Ying Tian,Yuan Xie,Zaixin Guo,Penghui Feng,Yang You,Qi Yu

Neurochemical research 48:2542-2551 PubMed37061657

2023

Dithiolethiones D3T and ACDT Protect Against Iron Overload-Induced Cytotoxicity and Serve as Ferroptosis Inhibitors in U-87 MG Cells.

Applications

Unspecified application

Species

Unspecified reactive species

Neha Kulkarni,Rajitha Gadde,Swati Betharia

Cancer cell international 23:5 PubMed36639654

2023

Heat shock protein 27 deficiency promotes ferrous ion absorption and enhances acyl-Coenzyme A synthetase long-chain family member 4 stability to promote glioblastoma cell ferroptosis.

Applications

Unspecified application

Species

Unspecified reactive species

Kai Zhang,Yue Wu,Guangliang Chen,Hao Wang,Yongsheng Liu,Youxin Zhou

View all publications

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Abcam Product Promise

我们致力于为您的研究提供高质量的试剂，为您科研的每一步提供支持。若我们的产品未能达到预期性能，我们向您提供 Abcam Product Promise 保障。

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For licensing inquiries, please contact partnerships@abcam.com

Anti-Ferroportin抗体[C8]

Anti-Ferroportin antibody [C8]

Western blot - Anti-Ferroportin antibody [C8] (AB239511)

关键信息

宿主种属

克隆

克隆号

亚型

轻链类型

不含载体蛋白

反应种属

应用

免疫原

反应性数据

性能和储存信息

形式

纯化工艺

纯化说明

存储溶液

运输条件

推荐的短期储存时间

推荐的短期储存条件

推荐的长期储存条件

分装信息

储存信息

产品实验方案

靶点信息

文献 (14)

Abcam Product Promise

Anti-Ferroportin抗体[C8]

Anti-Ferroportin antibody [C8]

Western blot - Anti-Ferroportin antibody [C8] (AB239511)

关键信息

宿主种属

克隆

克隆号

亚型

轻链类型

不含载体蛋白

反应种属

应用

免疫原

替代产品

Primary Antibodies

Primary Antibodies

Primary Antibodies

搭配使用产品

Assay Kits

Primary Antibodies

Primary Antibodies

Secondary Antibodies

Primary Antibodies

反应性数据

性能和储存信息

形式

纯化工艺

纯化说明

存储溶液

运输条件

推荐的短期储存时间

推荐的短期储存条件

推荐的长期储存条件

分装信息

储存信息

产品实验方案

靶点信息

文献 (14)

Abcam Product Promise