Anti-SLC39A1抗体(ab105416)
Key features and details
- Rabbit polyclonal to SLC39A1
- Suitable for: ICC/IF, IHC-P, WB
- Reacts with: Mouse, Human
- Isotype: IgG
概述
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产品名称
Anti-SLC39A1抗体 -
描述
兔多克隆抗体to SLC39A1 -
宿主
Rabbit -
特异性
At least two isoforms of SLC39A1 are known to exist; this antibody will recognize both isoforms. SLC39A1 antibody is predicted to not cross-react with other SLC39A1 family members. -
经测试应用
适用于: ICC/IF, IHC-P, WBmore details -
种属反应性
与反应: Mouse, Human -
免疫原
Synthetic peptide corresponding to a region of 16 amino acids near the amino terminus of Human SLC39A1 (NP_055252)
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阳性对照
- Mouse Kidney Tissue Lysate
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab105416于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| ICC/IF |
Use at an assay dependent concentration.
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| IHC-P |
Use at an assay dependent concentration.
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| WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 34 kDa.
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| 说明 |
|---|
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ICC/IF
Use at an assay dependent concentration. |
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IHC-P
Use at an assay dependent concentration. |
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WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 34 kDa. |
靶标
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功能
Mediates zinc uptake. May function as a major endogenous zinc uptake transporter in many cells of the body. Responsible for the rapid uptake and accumulation of physiologically effective zinc in prostate cells. -
组织特异性
Ubiquitous. Expressed in most adult and fetal tissues including the epidermis. -
序列相似性
Belongs to the ZIP transporter (TC 2.A.5) family. -
细胞定位
Cell membrane. Endoplasmic reticulum membrane. Shows a vesicular localization corresponding partially to the endoplasmic reticulum in several epithelial cell lines. - Information by UniProt
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数据库链接
- Entrez Gene: 27173 Human
- Entrez Gene: 30791 Mouse
- Omim: 604740 Human
- SwissProt: Q9NY26 Human
- SwissProt: Q9QZ03 Mouse
- Unigene: 7854 Human
- Unigene: 294709 Mouse
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别名
- hZIP1 antibody
- IRT1 antibody
- S39A1_HUMAN antibody
see all
图片
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Western blot - Anti-SLC39A1 antibody (ab105416)Lane 1 : Anti-SLC39A1 antibody (ab105416) at 1 µg/ml
Lane 2 : Anti-SLC39A1 antibody (ab105416) at 2 µg/ml
All lanes : Mouse kidney tissue lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 34 kDa
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (5)
ab105416 被引用在 5 文献中.
- Bogdanovic M et al. The ZIP3 Zinc Transporter Is Localized to Mossy Fiber Terminals and Is Required for Kainate-Induced Degeneration of CA3 Neurons. J Neurosci 42:2824-2834 (2022). PubMed: 35169020
- Zhang Q et al. Decreased SLC39A1 (Solute carrier family 39 member 1) expression predicts unfavorable prognosis in patients with early-stage hepatocellular carcinoma. Bioengineered 12:8147-8156 (2021). PubMed: 34615436
- Da W et al. Protective Role of Melatonin Against Postmenopausal Bone Loss via Enhancement of Citrate Secretion From Osteoblasts. Front Pharmacol 11:667 (2020). PubMed: 32508637
- Wang P et al. SLC39A1 contribute to malignant progression and have clinical prognostic impact in gliomas. Cancer Cell Int 20:573 (2020). PubMed: 33292262
- Dong X et al. GAS5 functions as a ceRNA to regulate hZIP1 expression by sponging miR-223 in clear cell renal cell carcinoma. Am J Cancer Res 8:1414-1426 (2018). PubMed: 30210913