Anti-SLC31A1 / CTR1抗体(ab133385)
Key features and details
- Rabbit polyclonal to SLC31A1 / CTR1
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-SLC31A1 / CTR1抗体
参阅全部 SLC31A1 / CTR1 一抗 -
描述
兔多克隆抗体to SLC31A1 / CTR1 -
宿主
Rabbit -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat, Rabbit, Horse, Chicken, Hamster, Cow, Dog, Turkey, Pig, Xenopus laevis, Monkey, Gorilla, Opossum, Common marmoset, Orangutan, Platypus, Elephant
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免疫原
Synthetic 16 amino acid peptide from internal region of Human SLC31A1/ CTR1
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阳性对照
- Human placenta tissue and Human lung (respiratory epithelium) tissue
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.4
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab133385于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P |
Use a concentration of 15 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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| 说明 |
|---|
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IHC-P
Use a concentration of 15 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
靶标
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功能
High-affinity, saturable copper transporter involved in dietary copper uptake. -
序列相似性
Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily. -
翻译后修饰
O-Glycosylation at Thr-27 protects from proteolytic cleavage in the N-terminal extracellular domain. -
细胞定位
Cell membrane. Localizes to the apical membrane in intestinal epithelial cells. - Information by UniProt
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数据库链接
- Entrez Gene: 100689094 Hamster
- Entrez Gene: 1317 Human
- Entrez Gene: 20529 Mouse
- Entrez Gene: 397186 Pig
- Entrez Gene: 171135 Rat
- Omim: 603085 Human
- SwissProt: O15431 Human
- SwissProt: Q8K211 Mouse
see all -
别名
- Copper transport 1 homolog antibody
- Copper transporter 1 antibody
- COPT1 antibody
see all
图片
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SLC31A1 / CTR1 antibody (ab133385)Immunohistochemical analysis of formalin-fixed, paraffin embedded Human placenta tissue labelling SLC31A1 / CTR1 with ab133385 at 15 µg/ml. Followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SLC31A1 / CTR1 antibody (ab133385)Immunohistochemical analysis of formalin-fixed, paraffin embedded Human lung, respiratory epithelium, tissue labelling SLC31A1 / CTR1 with ab133385 at 15 µg/ml. Followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
数据表及文件
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SDS download
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Datasheet download
文献 (4)
ab133385 被引用在 4 文献中.
- Zhang J et al. Molecular subtypes based on cuproptosis-related genes and tumor microenvironment infiltration characterization in ovarian cancer. Cancer Cell Int 22:328 (2022). PubMed: 36307842
- Wu G et al. ZNF711 down-regulation promotes CISPLATIN resistance in epithelial ovarian cancer via interacting with JHDM2A and suppressing SLC31A1 expression. EBioMedicine 71:103558 (2021). PubMed: 34521054
- Parmar A et al. In vivo [64Cu]CuCl2 PET imaging reveals activity of Dextran-Catechin on tumor copper homeostasis. Theranostics 8:5645-5659 (2018). PubMed: 30555570
- Xia Y et al. Prognostic value of copper transporter 1 expression in patients with clear cell renal cell carcinoma. Oncol Lett 14:5791-5800 (2017). PubMed: 29113209