重组Anti-SLC25A38抗体[EPBHMR1] (ab133614)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPBHMR1] to SLC25A38
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
概述
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产品名称
Anti-SLC25A38抗体[EPBHMR1]
参阅全部 SLC25A38 一抗 -
描述
兔单克隆抗体[EPBHMR1] to SLC25A38 -
宿主
Rabbit -
经测试应用
适用于: WBmore details
不适用于: Flow Cyt,ICC/IF,IHC-P or IP -
种属反应性
与反应: Human -
免疫原
Synthetic peptide within Human SLC25A38 aa 50-150. The exact sequence is proprietary.
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阳性对照
- TF-1 cell lysate
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常规说明
This antibody was developed as part of a collaboration between Epitomics, Sanford Burnham Medical Research Institute and the lab of Huaxi Xu.
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
存储溶液
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading...
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纯度
Tissue culture supernatant -
克隆
单克隆 -
克隆编号
EPBHMR1 -
同种型
IgG -
研究领域
相关产品
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Alternative Versions
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab133614于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB |
1/1000 - 1/10000. Detects a band of approximately 33 kDa (predicted molecular weight: 33 kDa).
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说明 |
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WB
1/1000 - 1/10000. Detects a band of approximately 33 kDa (predicted molecular weight: 33 kDa). |
靶标
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功能
Mitochondrial carrier required during erythropoiesis. Probably involved in the biosynthesis of heme, possibly by facilitating 5-aminolevulinate (ALA) production. May act by importing glycine into mitochondria or by exchanging glycine for ALA across the mitochondrial inner membrane. -
组织特异性
Preferentially expressed in erythroid cells. -
疾病相关
Anemia, sideroblastic, pyridoxine-refractory, autosomal recessive -
序列相似性
Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
Contains 3 Solcar repeats. -
细胞定位
Mitochondrion inner membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 54977 Human
- Omim: 610819 Human
- SwissProt: Q96DW6 Human
- Unigene: 369615 Human
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别名
- FLJ20551 antibody
- FLJ22703 antibody
- S2538_HUMAN antibody
see all
图片
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Anti-SLC25A38 antibody [EPBHMR1] (ab133614) at 1/1000 dilution + TF-1 cell lysate at 10 µg
Secondary
HRP labelled goat anti-rabbit at 1/2000 dilution
Predicted band size: 33 kDa
Observed band size: 33 kDa
数据表及文件
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SDS download
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Datasheet download
文献 (4)
ab133614 被引用在 4 文献中.
- Fan Z et al. SLC25A38 as a novel biomarker for metastasis and clinical outcome in uveal melanoma. Cell Death Dis 13:330 (2022). PubMed: 35411037
- Zhang C et al. Appoptosin Mediates Lesions Induced by Oxidative Stress Through the JNK-FoxO1 Pathway. Front Aging Neurosci 11:243 (2019). PubMed: 31551758
- Zhang C et al. Appoptosin interacts with mitochondrial outer-membrane fusion proteins and regulates mitochondrial morphology. J Cell Sci 129:994-1002 (2016). PubMed: 26813789
- Zhao Y et al. Appoptosin-Mediated Caspase Cleavage of Tau Contributes to Progressive Supranuclear Palsy Pathogenesis. Neuron 87:963-75 (2015). PubMed: 26335643