AB133614

重组Anti-SLC25A38抗体[EPBHMR1]

Anti-SLC25A38 antibody [EPBHMR1]

RabMAb
Recombinant
了解详情

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(5 Publications)

Rabbit Recombinant Monoclonal SLC25A38 antibody. Suitable for WB and reacts with Human samples. Cited in 5 publications.

查看别名

Mitochondrial glycine transporter, Appoptosin, Mitochondrial glycine transporter GlyC, Solute carrier family 25 member 38, SLC25A38

1 Images

Unknown

Western blot - Anti-SLC25A38 antibody [EPBHMR1] (AB133614)

All lanes:

Western blot - Anti-SLC25A38 antibody [EPBHMR1] (ab133614) at 1/1000 dilution

All lanes:

TF-1 cell lysate at 10 µg

Secondary

All lanes:

HRP labelled goat anti-rabbit at 1/2000 dilution

Predicted band size: 33 kDa

Observed band size: 33 kDa

false

不同偶联物与剂型 (1)

Carrier free

Anti-SLC25A38 antibody [EPBHMR1] - BSA and Azide free

关键信息

宿主种属

Rabbit

克隆

Monoclonal

克隆号

EPBHMR1

亚型

IgG

不含载体蛋白

反应种属

Human

应用

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }

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产品详情

This antibody was developed as part of a collaboration between Epitomics, Sanford Burnham Medical Research Institute and the lab of Huaxi Xu.

Species reactivity
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species.
Please contact us for more information.

Patented technology
Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

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性能和储存信息

形式

Liquid

纯度

Tissue culture supernatant

存储溶液

pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 0.05% BSA

运输条件

Blue Ice

储存信息

Stable for 12 months at -20°C

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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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靶点信息

Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the mitochondrial matrix. Required during erythropoiesis.. Plays a role as pro-apoptotic protein that induces caspase-dependent apoptosis.

See full target information SLC25A38

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文献 (5)

Recent publications for all applications. Explore the full list and refine your search

Nature communications 16:978 PubMed39856062

2025

SLC25A38 is required for mitochondrial pyridoxal 5'-phosphate (PLP) accumulation.

Applications

Unspecified application

Species

Unspecified reactive species

Izabella A Pena,Jeffrey S Shi,Sarah M Chang,Jason Yang,Samuel Block,Charles H Adelmann,Heather R Keys,Preston Ge,Shveta Bathla,Isabella H Witham,Grzegorz Sienski,Angus C Nairn,David M Sabatini,Caroline A Lewis,Nora Kory,Matthew G Vander Heiden,Myriam Heiman

Cell death & disease 13:330 PubMed35411037

2022

SLC25A38 as a novel biomarker for metastasis and clinical outcome in uveal melanoma.

Applications

Unspecified application

Species

Unspecified reactive species

Zhongyi Fan,Jingjing Duan,Pu Luo,Ling Shao,Qiong Chen,Xiaohua Tan,Lei Zhang,Xiaojie Xu

Frontiers in aging neuroscience 11:243 PubMed31551758

2019

Appoptosin Mediates Lesions Induced by Oxidative Stress Through the JNK-FoxO1 Pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Cuilin Zhang,Zhenqiu Tan,Yongzhuang Xie,Yingjun Zhao,Timothy Y Huang,Zhaoping Lu,Hong Luo,Dan Can,Huaxi Xu,Yun-Wu Zhang,Xian Zhang

Journal of cell science 129:994-1002 PubMed26813789

2016

Appoptosin interacts with mitochondrial outer-membrane fusion proteins and regulates mitochondrial morphology.

Applications

Unspecified application

Species

Unspecified reactive species

Cuilin Zhang,Zhun Shi,Lingzhi Zhang,Zehua Zhou,Xiaoyuan Zheng,Guiying Liu,Guojun Bu,Paul E Fraser,Huaxi Xu,Yun-Wu Zhang

Neuron 87:963-75 PubMed26335643

2015

Appoptosin-Mediated Caspase Cleavage of Tau Contributes to Progressive Supranuclear Palsy Pathogenesis.

Applications

Unspecified application

Species

Unspecified reactive species

Yingjun Zhao,I-Chu Tseng,Charles J Heyser,Edward Rockenstein,Michael Mante,Anthony Adame,Qiuyang Zheng,Timothy Huang,Xin Wang,Pharhad E Arslan,Paramita Chakrabarty,Chengbiao Wu,Guojun Bu,William C Mobley,Yun-Wu Zhang,Peter St George-Hyslop,Eliezer Masliah,Paul Fraser,Huaxi Xu

View all publications

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Abcam Product Promise

我们致力于为您的研究提供高质量的试剂，为您科研的每一步提供支持。若我们的产品未能达到预期性能，我们向您提供 Abcam Product Promise 保障。

详情请参阅我们的条款与条件。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

重组Anti-SLC25A38抗体[EPBHMR1]