Anti-Skp1抗体(ab41865)
Key features and details
- Rabbit polyclonal to Skp1
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Human
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术，可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-Skp1抗体
参阅全部 Skp1 一抗 -
描述
兔多克隆抗体to Skp1 -
宿主
Rabbit -
经测试应用
适用于: IHC-P, WBmore details -
种属反应性
与反应: Mouse, Human
预测可用于: Rat
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免疫原
Synthetic peptide within Human Skp1 aa 100 to the C-terminus (C terminal). The exact sequence is proprietary.
Database link: P63208 -
阳性对照
- Breast carcinoma.
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常规说明
This product is FOR RESEARCH USE ONLY. For commercial use, please contact partnerships@abcam.com.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.60
Preservative: 0.1% Sodium azide
Constituents: PBS, 1% BSA -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab41865于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P |
1/100. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
|
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| WB |
Use at an assay dependent concentration.
|
| 说明 |
|---|
|
IHC-P
1/100. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
|
WB
Use at an assay dependent concentration. |
靶标
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功能
Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. SCF(BTRC) mediates the ubiquitination of NFKBIA at 'Lys-21' and 'Lys-22'; the degradation frees the associated NFKB1-RELA dimer to translocate into the nucleus and to activate transcription. SCF(Cyclin F) directs ubiquitination of CP110. -
通路
Protein modification; protein ubiquitination. -
序列相似性
Belongs to the SKP1 family. - Information by UniProt
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数据库链接
- Entrez Gene: 6500 Human
- Entrez Gene: 21402 Mouse
- Entrez Gene: 287280 Rat
- Omim: 601434 Human
- SwissProt: P63208 Human
- SwissProt: Q9WTX5 Mouse
- SwissProt: Q6PEC4 Rat
- Unigene: 171626 Human
see all -
别名
- Cyclin A/CDK2 associated p19 antibody
- Cyclin A/CDK2 associated protein p19 antibody
- Cyclin-A/CDK2-associated protein p19 antibody
see all
图片
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Skp1 antibody (ab41865)Ab41865 staining human Skp1 in human breast carcinoma by immunohistochemistry using formalin fixed paraffin embedded tissue.
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Western blot - Anti-Skp1 antibody (ab41865)Anti-Skp1 antibody (ab41865) at 1/25 dilution + lysate prepared from NIH3T3 cells
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab41865 尚未被引用在任何文献中。