Anti-SHP1 (phospho Y564)抗体(ab79294)
Key features and details
- Rabbit polyclonal to SHP1 (phospho Y564)
- Suitable for: WB
- Reacts with: African green monkey
- Isotype: IgG
概述
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产品名称
Anti-SHP1 (phospho Y564)抗体
参阅全部 SHP1 一抗 -
描述
兔多克隆抗体to SHP1 (phospho Y564) -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: African green monkey -
免疫原
Synthetic peptide corresponding to Human SHP1 (phospho Y564).
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阳性对照
- Extracts from COS7 cells, treated with EGF (200ng/ml, 30mins)
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol, 0.87% Sodium chloride
Without Mg2+ and Ca2+ -
Concentration information loading... -
纯度
Immunogen affinity purified -
纯化说明
ab79294 is purified from rabbit antiserum by chromatography using an epitope specific phosphopeptide. The antibody against non phosphopeptide was removed by chromatography using non phosphopeptide corresponding to the phosphorylation site. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab79294于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/500 - 1/1000. Predicted molecular weight: 68 kDa.
|
| 说明 |
|---|
|
WB
1/500 - 1/1000. Predicted molecular weight: 68 kDa. |
靶标
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功能
Plays a key role in hematopoiesis. This PTPase activity may directly link growth factor receptors and other signaling proteins through protein-tyrosine phosphorylation. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. -
组织特异性
Isoform 1 is expressed in hematopoietic cells. Isoform 2 is expressed in non-hematopoietic cells. -
序列相似性
Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
Contains 2 SH2 domains.
Contains 1 tyrosine-protein phosphatase domain. -
翻译后修饰
Phosphorylated on serine and tyrosine residues. -
细胞定位
Cytoplasm. Nucleus. In neurons, translocates into the nucleus after treatment with angiotensin II. - Information by UniProt
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别名
- 70Z-SHP antibody
- EC 3.1.3.48 antibody
- HCP antibody
see all
图片
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Western blot - Anti-SHP1 (phospho Y564) antibody (ab79294)All lanes : Anti-SHP1 (phospho Y564) antibody (ab79294) at 1/1000 dilution
Lane 1 : extracts from COS7 cells, treated with EGF (200 ng/ml, 30 mins)
Lane 2 : extracts from COS7 cells, treated with EGF (200 ng/ml, 30 mins) with immunising peptide at 10 µg
Lysates/proteins at 30 µg per lane.
Predicted band size: 68 kDa
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab79294 尚未被引用在任何文献中。