Anti-SHOX2抗体[1D1] (ab55740)
![Western blot - Anti-SHOX2 antibody [1D1] (ab55740)](https://www.abcam.cn/ps/products/55/ab55740/Images/ab55740-358926-anti-shox2-antibody-westernblot-recombinant-protein.jpg "Western blot - Anti-SHOX2 antibody [1D1] (ab55740)")
Key features and details
- Mouse monoclonal [1D1] to SHOX2
- Suitable for: WB, IHC-Fr
- Reacts with: Rat, Human, Recombinant fragment
- Isotype: IgG2a
概述
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产品名称
Anti-SHOX2抗体[1D1]
参阅全部 SHOX2 一抗 -
描述
小鼠单克隆抗体[1D1] to SHOX2 -
宿主
Mouse -
经测试应用
适用于: WB, IHC-Frmore details -
种属反应性
与反应: Rat, Human, Recombinant fragment -
免疫原
Recombinant fragment corresponding to Human SHOX2 aa 117-204.
Sequence:SPELKDRKDDAKGMEDEGQTKIKQRRSRTNFTLEQLNELERLFDETHYPD AFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQLHK
Database link: O60902 -
阳性对照
- WB: Human liver tissue lysat; PC-12 cell lysate
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常规说明
This product was changed from ascites to tissue culture supernatant on 16/Oct/2019. Lot numbers higher than GR3303529 are from tissue culture supernatant. Please note that the dilutions may need to be adjusted accordingly. If you have any questions, please do not hesitate to contact our scientific support team.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.40
Constituent: PBS -
Concentration information loading... -
纯度
Tissue culture supernatant -
克隆
单克隆 -
克隆编号
1D1 -
同种型
IgG2a -
轻链类型
kappa -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab55740于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 35 kDa.
|
|
| IHC-Fr | (1) |
Use at an assay dependent concentration.
|
| 说明 |
|---|
|
WB
Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 35 kDa. |
|
IHC-Fr
Use at an assay dependent concentration. |
靶标
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功能
May be a growth regulator and have a role in specifying neural systems involved in processing somatosensory information, as well as in face and body structure formation. -
组织特异性
Expressed in heart, skeletal muscle, liver, lung, bone marrow fibroblast, pancreas and placenta. -
序列相似性
Belongs to the paired homeobox family. Bicoid subfamily.
Contains 1 homeobox DNA-binding domain. -
发展阶段
Expressed during cranofacial development as well as in heart. -
细胞定位
Nucleus. - Information by UniProt
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数据库链接
- Entrez Gene: 6474 Human
- Entrez Gene: 25546 Rat
- Omim: 602504 Human
- SwissProt: O60902 Human
- SwissProt: O35750 Rat
- Unigene: 55967 Human
- Unigene: 11258 Rat
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别名
- Homeobox protein Og12X antibody
- OG 12 antibody
- OG 12X antibody
see all
图片
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Western blot - Anti-SHOX2 antibody [1D1] (ab55740)Anti-SHOX2 antibody [1D1] (ab55740) + Recombinant SHOX2 Protein.
Predicted band size: 35 kDaThis image was generated using the ascites version of the product.
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![Western blot - Anti-SHOX2 antibody [1D1] (ab55740)](https://www.abcam.cn/ps/products/55/ab55740/Images/ab55740-69114-anti-shox2-antibody-western-blot.jpg)
Western blot - Anti-SHOX2 antibody [1D1] (ab55740)SHOX2 antibody (ab55740) at 1ug/lane + PC-12 cell lysate at 25ug/lane.
This image was generated using the ascites version of the product.
数据表及文件
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SDS download
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Datasheet download
文献 (15)
ab55740 被引用在 15 文献中.
- Yin L et al. RA signaling pathway combined with Wnt signaling pathway regulates human-induced pluripotent stem cells (hiPSCs) differentiation to sinus node-like cells. Stem Cell Res Ther 13:324 (2022). PubMed: 35851424
- Wiesinger A et al. A single cell transcriptional roadmap of human pacemaker cell differentiation. Elife 11:N/A (2022). PubMed: 36217819
- Li J et al. Molecular and electrophysiological evaluation of human cardiomyocyte subtypes to facilitate generation of composite cardiac models. J Tissue Eng 13:20417314221127908 (2022). PubMed: 36277058
- Ye F et al. TNF-α suppresses SHOX2 expression via NF-κB signaling pathway and promotes intervertebral disc degeneration and related pain in a rat model. J Orthop Res 39:1745-1754 (2021). PubMed: 32816304
- Baudouin C et al. Generation and characterization of a tamoxifen-inducible Vsx1-CreERT2 line to target V2 interneurons in the mouse developing spinal cord. Genesis 59:e23435 (2021). PubMed: 34080769