Anti-SFRS4/SRSF4抗体(ab73893)
Key features and details
- Rabbit polyclonal to SFRS4/SRSF4
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-SFRS4/SRSF4抗体
参阅全部 SFRS4/SRSF4 一抗 -
描述
兔多克隆抗体to SFRS4/SRSF4 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Mouse
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免疫原
Synthetic peptide corresponding to Human SFRS4/SRSF4 (internal sequence).
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阳性对照
- Extracts from LoVo cells.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, PBS
Without Mg2+ and Ca2+ -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab73893于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/500 - 1/1000. Predicted molecular weight: 57 kDa.
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| 说明 |
|---|
|
WB
1/500 - 1/1000. Predicted molecular weight: 57 kDa. |
靶标
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功能
A probable role in alternative splice site selection during pre-mRNA splicing. -
序列相似性
Belongs to the splicing factor SR family.
Contains 2 RRM (RNA recognition motif) domains. -
翻译后修饰
Extensively phosphorylated on serine residues in the RS domain. -
细胞定位
Nucleus speckle. - Information by UniProt
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数据库链接
- Entrez Gene: 6429 Human
- Entrez Gene: 57317 Mouse
- Omim: 601940 Human
- SwissProt: Q08170 Human
- SwissProt: Q8VE97 Mouse
- Unigene: 469970 Human
- Unigene: 2478 Mouse
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别名
- arginine/serine-rich 4 antibody
- Pre mRNA splicing factor SRP75 antibody
- Pre-mRNA-splicing factor SRP75 antibody
see all
图片
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Western blot - Anti-SFRS4/SRSF4 antibody (ab73893)All lanes : Anti-SFRS4/SRSF4 antibody (ab73893) at 1/500 dilution
Lane 1 : extracts from LoVo cells
Lane 2 : extracts from LoVo cells with immunizing peptide at 5 µg
Lysates/proteins at 20 µg per lane.
Predicted band size: 57 kDa
Observed band size: 57 kDa
Additional bands at: 20 kDa, 48 kDa. We are unsure as to the identity of these extra bands.
数据表及文件
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SDS download
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Datasheet download
文献 (3)
ab73893 被引用在 3 文献中.
- Breitkopf SB et al. Serial-omics of P53-/-, Brca1-/- Mouse Breast Tumor and Normal Mammary Gland. Sci Rep 7:14503 (2017). PubMed: 29109428
- Guo H et al. Androgen receptor binding to an androgen-responsive element in the promoter of the Srsf4 gene inhibits its expression in mouse Sertoli cells. Mol Reprod Dev 82:976-85 (2015). PubMed: 26308373
- Gautrey HL & Tyson-Capper AJ Regulation of Mcl-1 by SRSF1 and SRSF5 in cancer cells. PLoS One 7:e51497 (2012). WB ; Human . PubMed: 23284704