Anti-Serotonin抗体(ab66047)
Key features and details
- Goat polyclonal to Serotonin
- Suitable for: IHC-FoFr
- Reacts with: Species independent
- Isotype: IgG
概述
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产品名称
Anti-Serotonin抗体
参阅全部 Serotonin 一抗 -
描述
山羊多克隆抗体to Serotonin -
宿主
Goat -
经测试应用
适用于: IHC-FoFrmore details -
种属反应性
与反应: Species independent -
免疫原
Serotonin whole molecule conjugated to BSA with paraformaldehyde.
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常规说明
If the product is lyophilized upon delivery, dilute with phosphate buffer or Tris buffer at dilutions no higher than 1/10, aliquot and freeze at -15° C or lower. Antibody can be stored for up to six months if handled as described above.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
Constituent: Whole serum -
Concentration information loading... -
纯度
Whole antiserum -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Related Products
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab66047于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-FoFr |
1/400 - 1/800. When using Biotin/Streptavidin-HRP Technique dilution of 1/5000 - 1/10000.
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| 说明 |
|---|
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IHC-FoFr
1/400 - 1/800. When using Biotin/Streptavidin-HRP Technique dilution of 1/5000 - 1/10000. |
靶标
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相关性
Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine neurotransmitter synthesised in serotonergic neurons in the central nervous system and enterochromaffin cells in the gastrointestinal tract. Serotonin plays an important part in the biochemistry of depression, migraine, bipolar disorder and anxiety. It is also believed to be influential on sexuality and appetite. 5-HT is generally thought not to be released from synaptic terminal buttons in the manner of classical neurotransmission but from serotonergic varacosities into the extra neuronal space. From here it is free to diffuse over a relatively large region of space (>20µm) and activate 5-HT receptors located on the dendrites, cell bodies and presynaptic terminals of adjacent neurons. Serotonergic action is terminated primarily via uptake of 5-HT from the synapse. This is through the specific monoamine transporter for 5-HT, 5-HT reuptake transporter, on the presynaptic neuron. The pharmacology of 5-HT is extremely complex, with its actions being mediated by a large and diverse range of 5-HT receptors. -
细胞定位
Cytoplasmic and Secreted -
别名
- 5 hydroxytryptamine antibody
- 5HT antibody
图片
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Immunohistochemistry (PFA perfusion fixed frozen sections) - Anti-Serotonin antibody (ab66047)ab66407 staining of rat hypothalamus using 4+ biotin-streptavidin/HRP staing at 1/4000.
实验方案
数据表及文件
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Datasheet download
文献 (68)
ab66047 被引用在 68 文献中.
- Widmayer P et al. Short-term high fat feeding induces inflammatory responses of tuft cells and mucosal barrier cells in the murine stomach. Histol Histopathol 38:273-286 (2023). PubMed: 35904321
- Cheung A et al. Neurexins in serotonergic neurons regulate neuronal survival, serotonin transmission, and complex mouse behaviors. Elife 12:N/A (2023). PubMed: 36695811
- Hayashi M et al. Enteroendocrine cell lineages that differentially control feeding and gut motility. Elife 12:N/A (2023). PubMed: 36810133
- Xiao M et al. The gut-brain axis: Effect of electroacupuncture pretreatment on learning, memory, and JNK signaling in D-galactose-induced AD-like rats. Iran J Basic Med Sci 26:532-539 (2023). PubMed: 37051108
- Song S et al. Genetic Architecture and Functional Implications of the CSF-Contacting Nucleus. Neurosci Bull 39:1638-1654 (2023). PubMed: 37405574
