Anti-SEMA5A抗体(ab51957)
Key features and details
- Goat polyclonal to SEMA5A
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-SEMA5A抗体
参阅全部 SEMA5A 一抗 -
描述
山羊多克隆抗体to SEMA5A -
宿主
Goat -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat, Cow, Dog
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免疫原
Synthetic peptide corresponding to SEMA5A aa 91-110 (internal sequence).
Sequence:DEATKKACYSKGKS
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.5% BSA, Tris buffered saline -
Concentration information loading... -
纯度
Immunogen affinity purified -
纯化说明
ab51957 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab51957于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P |
Use a concentration of 4 - 6 µg/ml.
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| 说明 |
|---|
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IHC-P
Use a concentration of 4 - 6 µg/ml. |
靶标
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相关性
Members of the semaphorin protein family are involved in axonal guidance during neural development. Semaphorin 5a is thought to have a bifunctional role in axon guidance, exerting both attractive and inhibitory effects on developing axons associated with limbic function. The thrombospondin repeats of Semaphorin 5a physically interact with both heparan sulfate proteoglycans and chondroitin sulfate proteoglycans, inducing attractive and inhibitory guidance cues, respectively. The biological responses to Semaphorin 5a are induced through binding to its high-affinity receptor, plexin B3, triggering intracellular signaling through Met. -
细胞定位
Membrane; single-pass type I membrane protein -
数据库链接
- Entrez Gene: 9037 Human
- Entrez Gene: 20356 Mouse
- Omim: 609297 Human
- SwissProt: Q13591 Human
- SwissProt: Q62217 Mouse
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别名
- SEMA5A antibody
- SEMAF antibody
- Semaphorin F antibody
图片
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SEMA5A antibody (ab51957)
ab51957 at 4µg/ml staining SEMA5A in Human kidney tissue by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections). Steamed antigen retrieval with citrate buffer pH 6 was performed. Antibody was detected by HRP-staining.
数据表及文件
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Datasheet download
文献 (1)
ab51957 被引用在 1 文献中.
- Monticone M et al. Identification of a novel set of genes reflecting different in vivo invasive patterns of human GBM cells. BMC Cancer 12:358 (2012). ICC/IF ; Human . PubMed: 22901239
