Anti-SCNN1B抗体(ab172276)
Key features and details
- Mouse polyclonal to SCNN1B
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-SCNN1B抗体
参阅全部 SCNN1B 一抗 -
描述
小鼠多克隆抗体to SCNN1B -
宿主
Mouse -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Rabbit
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免疫原
Recombinant full length protein within Human SCNN1B aa 1 to the C-terminus. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
Database link: AAH36352.2 -
阳性对照
- Recombinant Human SCNN1B protein (ab132248) can be used as a positive control in WB. SCNN1B transfected 293T cell line lysate.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.4
Constituent: 100% PBS -
Concentration information loading... -
纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab172276于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use a concentration of 1 µg/ml. Predicted molecular weight: 73 kDa.
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| 说明 |
|---|
|
WB
Use a concentration of 1 µg/ml. Predicted molecular weight: 73 kDa. |
靶标
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功能
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception. -
疾病相关
Pseudohypoaldosteronism 1, autosomal recessive
Liddle syndrome
Bronchiectasis with or without elevated sweat chloride 1 -
序列相似性
Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. SCNN1B subfamily. -
翻译后修饰
Phosphorylated on serine and threonine residues. -
细胞定位
Apical cell membrane. Apical membrane of epithelial cells. - Information by UniProt
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数据库链接
- Entrez Gene: 6338 Human
- Omim: 600760 Human
- SwissProt: P51168 Human
- SwissProt: O97742 Rabbit
- Unigene: 414614 Human
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别名
- Amiloride sensitive sodium channel subunit beta antibody
- Amiloride-sensitive sodium channel subunit beta antibody
- Beta NaCH antibody
see all
图片
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Western blot - Anti-SCNN1B antibody (ab172276)All lanes : Anti-SCNN1B antibody (ab172276) at 1 µg/ml
Lane 1 : SCNN1B transfected 293T cell line lysate
Lane 2 : 293T cell line lysate (non-transfected)
Lysates/proteins at 15 µl per lane.
Secondary
All lanes : Goat anti-mouse HRP conjugated antibody at 1/2500 dilution
Developed using the ECL technique.
Predicted band size: 73 kDa
数据表及文件
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Datasheet download
文献 (0)
ab172276 尚未被引用在任何文献中。
