Anti-SCARA5抗体(ab118894)
Key features and details
- Rabbit polyclonal to SCARA5
- Suitable for: ICC, ELISA, WB, IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-SCARA5抗体
参阅全部 SCARA5 一抗 -
描述
兔多克隆抗体to SCARA5 -
宿主
Rabbit -
经测试应用
适用于: ICC, ELISA, WB, IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse
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免疫原
17 amino acid synthetic peptide near the carboxy terminus of Human SCARA5.
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阳性对照
- Human Small Intestine tissue; Human liver tissue lysate.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.4
Preservative: 0.02% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab118894于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| ICC |
Use at an assay dependent concentration.
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| ELISA |
Use at an assay dependent concentration.
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| WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 54 kDa.
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| IHC-P |
Use a concentration of 5 µg/ml.
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| 说明 |
|---|
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ICC
Use at an assay dependent concentration. |
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ELISA
Use at an assay dependent concentration. |
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WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 54 kDa. |
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IHC-P
Use a concentration of 5 µg/ml. |
靶标
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功能
Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Binds preferrentially ferritin light chain (FTL) compared to heavy chain (FTH1). -
序列相似性
Belongs to the SCARA5 family.
Contains 1 collagen-like domain.
Contains 1 SRCR domain. -
细胞定位
Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 286133 Human
- Entrez Gene: 71145 Mouse
- Omim: 611306 Human
- SwissProt: Q6ZMJ2 Human
- SwissProt: Q8K299 Mouse
- Unigene: 591833 Human
- Unigene: 83840 Mouse
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形式
There are 4 isoforms produced by alternative splicing. -
别名
- FLJ23907 antibody
- MGC45780 antibody
- NET33 antibody
see all
图片
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Western blot - Anti-SCARA5 antibody (ab118894)Anti-SCARA5 antibody (ab118894) at 1 µg/ml + Human liver tissue lysate
Predicted band size: 54 kDa -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SCARA5 antibody (ab118894)ab118894t 5µg/ml, staining SCARA5 in Formalin-fixed, Paraffin-embedded Human Small intestine tissue by Immunohistochemistry.
数据表及文件
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SDS download
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Datasheet download
文献 (9)
ab118894 被引用在 9 文献中.
- Flockerzi FA et al. SCARA5 Is Overexpressed in Prostate Cancer and Linked to Poor Prognosis. Diagnostics (Basel) 13:N/A (2023). PubMed: 37443605
- Liu SC et al. BMSC-derived exosomal lncRNA PTENP1 suppresses the malignant phenotypes of bladder cancer by upregulating SCARA5 expression. Cancer Biol Ther 23:1-13 (2022). PubMed: 35998226
- Peng Q et al. The Novel Methylation Biomarker SCARA5 Sensitizes Cancer Cells to DNA Damage Chemotherapy Drugs in NSCLC. Front Oncol 11:666589 (2021). PubMed: 34150631
- de Seny D et al. New Proteins Contributing to Immune Cell Infiltration and Pannus Formation of Synovial Membrane from Arthritis Diseases. Int J Mol Sci 23:N/A (2021). PubMed: 35008858
- Haddad Y et al. Norepinephrine transporter-derived homing peptides enable rapid endocytosis of drug delivery nanovehicles into neuroblastoma cells. J Nanobiotechnology 18:95 (2020). PubMed: 32660596
- Indra R et al. Ellipticine-loaded apoferritin nanocarrier retains DNA adduct-based cytochrome P450-facilitated toxicity in neuroblastoma cells. Toxicology 419:40-54 (2019). PubMed: 30914192
- Dostalova S et al. Prostate-Specific Membrane Antigen-Targeted Site-Directed Antibody-Conjugated Apoferritin Nanovehicle Favorably Influences In Vivo Side Effects of Doxorubicin. Sci Rep 8:8867 (2018). PubMed: 29891921
- Cutrin JC et al. Cancer cell death induced by ferritins and the peculiar role of their labile iron pool. Oncotarget 9:27974-27984 (2018). PubMed: 29963255
- Liu J et al. Suppression of SCARA5 by Snail1 is essential for EMT-associated cell migration of A549 cells. Oncogenesis 2:e73 (2013). WB . PubMed: 24061576