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AB22055

Anti-SARS Envelope蛋白抗体- Coronavirus

Anti-SARS Envelope Protein antibody - Coronavirus

4

(2 Reviews)

|

(1 Publication)

Rabbit Polyclonal VEMP antibody. Suitable for WB and reacts with SARS-CoV samples. Cited in 1 publication.
1 Images
Western blot - Anti-SARS Envelope Protein antibody - Coronavirus (AB22055)
  • WB

Unknown

Western blot - Anti-SARS Envelope Protein antibody - Coronavirus (AB22055)

All lanes:

Western blot - Anti-SARS Envelope Protein antibody - Coronavirus (ab22055) at 1 µg/mL

Observed band size: 16 kDa,32 kDa

false

关键信息

宿主种属

Rabbit

克隆

Polyclonal

亚型

IgG

不含载体蛋白

No

反应种属

SARS-CoV

应用

WB

applications

反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "SARS-CoV": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>" } } }

产品详情

Applications overview

Tick: Tested and Guaranteed to work X: Will not work —: No data Reviews: Customers have been successful and shared their AbReview

<img src="https://www.abcam.com/ps/Products/22/ab22055/Images/ab22055-394526-applications-overview.jpg" height="125" width="675">

性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Protein G
存储溶液
pH: 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 0.2% Gelatin
运输条件
Blue Ice
推荐的短期储存时间
1-2 weeks
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle

补充信息

This supplementary information is collated from multiple sources and compiled automatically.

The SARS Envelope Protein also known as E protein plays an essential role in the mechanical structure and function of the coronavirus. The protein has a mass of approximately 8.4 kDa and is expressed in the envelope of the virus. It functions as a viroporin creating ion channels that are important for the virus's lifecycle. These channels facilitate the transport of ions across the viral membrane contributing to the virus's assembly and budding processes.
Biological function summary

The SARS Envelope Protein exhibits significant functionality in viral pathogenesis and host interaction. It forms part of a larger protein complex in the viral envelope works alongside other structural proteins like the membrane (M) protein and nucleocapsid (N) protein. Through these actions the E protein influences coronavirus virulence assisting in virus-host interactions and the evasion of the host immune response.

Pathways

The SARS Envelope Protein actively participates in viral replication and assembly pathways. It interacts with host cell machinery to modulate viral and host processes important for replication. It also potentially influences the NF-kB signaling pathway which can affect host inflammation response. Related proteins include the spike (S) protein which helps the virus attach and enter host cells indicating a combined effort in infection spread.

The SARS Envelope Protein has a direct connection to illnesses such as COVID-19 and Severe Acute Respiratory Syndrome (SARS). The protein's role in viral assembly and immune evasion links it to the severity and transmission of these diseases. It is also connected to the IFN path where it can interfere with the host's interferon response a critical aspect of antiviral defense. These interactions make the SARS Envelope Protein a potential target for therapeutic interventions.

产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Journal of immunology (Baltimore, Md. : 1950) 176:2346-56 PubMed16455992

2006

CCL5 modulates pneumococcal immunity and carriage.

Applications

Unspecified application

Species

Unspecified reactive species

Ravichandran Palaniappan,Shailesh Singh,Udai P Singh,Rajesh Singh,Edwin W Ades,David E Briles,Susan K Hollingshead,Walter Royal,Jacquelyn S Sampson,Jonathan K Stiles,Dennis D Taub,James W Lillard
View all publications

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