Anti-SAP102抗体(ab3438)
Key features and details
- Rabbit polyclonal to SAP102
- Suitable for: IHC-Fr, WB
- Reacts with: Rat
- Isotype: IgG
概述
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产品名称
Anti-SAP102抗体
参阅全部 SAP102 一抗 -
描述
兔多克隆抗体to SAP102 -
宿主
Rabbit -
特异性
We have data to indicate that this antibody may not cross react with Mouse. However, this has not been conclusively tested and expression levels may vary in certain cell lines/tissues. -
经测试应用
适用于: IHC-Fr, WBmore details -
种属反应性
与反应: Rat
预测可用于: Mouse, Human
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免疫原
Synthetic peptide corresponding to Rat SAP102 aa 83-100.
Sequence:GPVPPKPVPGKNTPKLNG
(Peptide available asab5841) -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
Preservative: 0.05% Sodium azide
Constituents: 99% PBS, 0.1% BSA -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-Fr |
Use a concentration of 10 µg/ml.
|
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| WB | (2) |
Use a concentration of 3 µg/ml.
|
| 说明 |
|---|
|
IHC-Fr
Use a concentration of 10 µg/ml. |
|
WB
Use a concentration of 3 µg/ml. |
靶标
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功能
Required for learning most likely through its role in synaptic plasticity following NMDA receptor signaling. -
疾病相关
Defects in DLG3 are the cause of mental retardation X-linked type 90 (MRX90) [MIM:300189]. Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs. -
序列相似性
Belongs to the MAGUK family.
Contains 1 guanylate kinase-like domain.
Contains 3 PDZ (DHR) domains.
Contains 1 SH3 domain. - Information by UniProt
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数据库链接
- Entrez Gene: 1741 Human
- Entrez Gene: 53310 Mouse
- Entrez Gene: 58948 Rat
- Omim: 300189 Human
- SwissProt: Q92796 Human
- SwissProt: P70175 Mouse
- SwissProt: Q62936 Rat
- Unigene: 726128 Human
see all -
别名
- bA291O7.3 antibody
- bA291O7.3 discs large Drosophila homolog 3 neuroendocrine dlg antibody
- Discs large Drosophila homolog 3 antibody
see all
图片
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Western blot - Anti-SAP102 antibody (ab3438)
Western blot of SAP102 on extract from COS cells transfected with rat SAP102 using ab3438.
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Immunohistochemistry (Frozen sections) - Anti-SAP102 antibody (ab3438)Immunohistochemistry (Frozen sections) analysis of Ammon's Horn and the dentate gyrus of the rat hippocampus labeling SAP102 with ab3438.
数据表及文件
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SDS download
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Datasheet download
文献 (5)
ab3438 被引用在 5 文献中.
- Chen FB et al. LINC01315 Impairs microRNA-211-Dependent DLG3 Downregulation to Inhibit the Development of Oral Squamous Cell Carcinoma. Front Oncol 10:556084 (2020). PubMed: 33117688
- Deng HS et al. Phosphoproteomic profiling of oxycodone-treated spinal cord of rats with cancer-induced bone pain. Mol Med Rep 20:4695-4705 (2019). PubMed: 31702022
- Risher ML et al. Adolescent intermittent alcohol exposure: persistence of structural and functional hippocampal abnormalities into adulthood. Alcohol Clin Exp Res 39:989-97 (2015). PubMed: 25916839
- Rastaldi MP et al. Glomerular podocytes contain neuron-like functional synaptic vesicles. FASEB J 20:976-8 (2006). PubMed: 16585060
- Jensen TP et al. Expression of plasma membrane Ca2+ ATPase family members and associated synaptic proteins in acute and cultured organotypic hippocampal slices from rat. Brain Res Dev Brain Res 152:129-36 (2004). WB ; Rat . PubMed: 15351500