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Neuroscience Neurotransmission Intracellular Signaling Adapters

Anti-SAP102抗体(ab3438)

  • Datasheet
  • SDS
Reviews (3) Submit a question References (5)

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Western blot - Anti-SAP102 antibody (ab3438)
  • Immunohistochemistry (Frozen sections) - Anti-SAP102 antibody (ab3438)

Key features and details

  • Rabbit polyclonal to SAP102
  • Suitable for: IHC-Fr, WB
  • Reacts with: Rat
  • Isotype: IgG

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概述

  • 产品名称

    Anti-SAP102抗体
    参阅全部 SAP102 一抗
  • 描述

    兔多克隆抗体to SAP102
  • 宿主

    Rabbit
  • 特异性

    We have data to indicate that this antibody may not cross react with Mouse. However, this has not been conclusively tested and expression levels may vary in certain cell lines/tissues.
  • 经测试应用

    适用于: IHC-Fr, WBmore details
  • 种属反应性

    与反应: Rat
    预测可用于: Mouse, Human
  • 免疫原

    Synthetic peptide corresponding to Rat SAP102 aa 83-100.
    Sequence:

    GPVPPKPVPGKNTPKLNG


    (Peptide available as ab5841)
    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
  • 常规说明

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

性能

  • 形式

    Liquid
  • 存放说明

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液

    Preservative: 0.05% Sodium azide
    Constituents: 99% PBS, 0.1% BSA
  • Concentration information loading...
  • 纯度

    Immunogen affinity purified
  • 克隆

    多克隆
  • 同种型

    IgG
  • 研究领域

    • Neuroscience
    • Neurotransmission
    • Intracellular Signaling
    • Adapters
    • Neuroscience
    • Cell Type Marker
    • Neuron marker
    • Dendrite marker
    • Neuroscience
    • Cell Type Marker
    • Neuron marker
    • Synapse marker
    • Neuroscience
    • Processes

相关产品

  • Compatible Secondaries

    • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
    • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
  • Isotype control

    • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)

应用

The Abpromise guarantee

Abpromise™承诺保证使用ab3438于以下的经测试应用

“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。

应用 Ab评论 说明
IHC-Fr
Use a concentration of 10 µg/ml.
WB (2)
Use a concentration of 3 µg/ml.
说明
IHC-Fr
Use a concentration of 10 µg/ml.
WB
Use a concentration of 3 µg/ml.

靶标

  • 功能

    Required for learning most likely through its role in synaptic plasticity following NMDA receptor signaling.
  • 疾病相关

    Defects in DLG3 are the cause of mental retardation X-linked type 90 (MRX90) [MIM:300189]. Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs.
  • 序列相似性

    Belongs to the MAGUK family.
    Contains 1 guanylate kinase-like domain.
    Contains 3 PDZ (DHR) domains.
    Contains 1 SH3 domain.
  • Target information above from: UniProt accession Q92796 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • 数据库链接

    • Entrez Gene: 1741 Human
    • Entrez Gene: 53310 Mouse
    • Entrez Gene: 58948 Rat
    • Omim: 300189 Human
    • SwissProt: Q92796 Human
    • SwissProt: P70175 Mouse
    • SwissProt: Q62936 Rat
    • Unigene: 726128 Human
    • Unigene: 4615 Mouse
    • Unigene: 10238 Rat
    see all
  • 别名

    • bA291O7.3 antibody
    • bA291O7.3 discs large Drosophila homolog 3 neuroendocrine dlg antibody
    • Discs large Drosophila homolog 3 antibody
    • Discs large homolog 3 neuroendocrine dlg Drosophila antibody
    • Discs large homolog 3 antibody
    • Discs large homolog 3 Drosophila antibody
    • Discs, large homolog 3 (Drosophila) antibody
    • Disks large homolog 3 antibody
    • DLG 3 antibody
    • Dlg3 antibody
    • DLG3_HUMAN antibody
    • KIAA1232 antibody
    • mKIAA1232 antibody
    • MRX 90 antibody
    • MRX antibody
    • MRX90 antibody
    • NE Dlg antibody
    • NEDLG antibody
    • Neuroendocrine dlg antibody
    • Neuroendocrine-DLG antibody
    • OTTHUMP00000023475 antibody
    • OTTHUMP00000023476 antibody
    • OTTHUMP00000023477 antibody
    • SAP 102 antibody
    • SAP-102 antibody
    • SAP102 antibody
    • Synapse associated protein 102 antibody
    • Synapse-associated protein 102 antibody
    • XLMR antibody
    see all

图片

  • Western blot - Anti-SAP102 antibody (ab3438)
    Western blot - Anti-SAP102 antibody (ab3438)

    Western blot of SAP102 on extract from COS cells transfected with rat SAP102 using ab3438.

  • Immunohistochemistry (Frozen sections) - Anti-SAP102 antibody (ab3438)
    Immunohistochemistry (Frozen sections) - Anti-SAP102 antibody (ab3438)

    Immunohistochemistry (Frozen sections) analysis of Ammon's Horn and the dentate gyrus of the rat hippocampus labeling SAP102 with ab3438.

实验方案

  • Immunohistochemistry protocols
  • Western blot protocols

Click here to view the general protocols

数据表及文件

  • SDS download

  • Datasheet download

    Download

文献 (5)

发表研究结果有使用 ab3438?请让我们知道,以便我们可以引用本数据表中的参考文章。

ab3438 被引用在 5 文献中.

  • Chen FB  et al. LINC01315 Impairs microRNA-211-Dependent DLG3 Downregulation to Inhibit the Development of Oral Squamous Cell Carcinoma. Front Oncol 10:556084 (2020). PubMed: 33117688
  • Deng HS  et al. Phosphoproteomic profiling of oxycodone-treated spinal cord of rats with cancer-induced bone pain. Mol Med Rep 20:4695-4705 (2019). PubMed: 31702022
  • Risher ML  et al. Adolescent intermittent alcohol exposure: persistence of structural and functional hippocampal abnormalities into adulthood. Alcohol Clin Exp Res 39:989-97 (2015). PubMed: 25916839
  • Rastaldi MP  et al. Glomerular podocytes contain neuron-like functional synaptic vesicles. FASEB J 20:976-8 (2006). PubMed: 16585060
  • Jensen TP  et al. Expression of plasma membrane Ca2+ ATPase family members and associated synaptic proteins in acute and cultured organotypic hippocampal slices from rat. Brain Res Dev Brain Res 152:129-36 (2004). WB ; Rat . PubMed: 15351500

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1-3 of 3 Abreviews or Q&A

Immunocytochemistry/ Immunofluorescence abreview for Anti-SAP102 antibody

Below Average
Abreviews
Abreviews
abreview image
Application
Immunocytochemistry/ Immunofluorescence
Sample
Rat Cell (Primary neuronal cultures)
Permeabilization
Yes - 0.25% Triton PBS
Specification
Primary neuronal cultures
Blocking step
BSA as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 10% · Temperature: RT°C
Fixative
Paraformaldehyde
Read More
The reviewer received a reward from Abcam’s Loyalty Program in thanks for submitting this Abreview and for helping the scientific community make better-informed decisions.

Abcam user community

Verified customer

提交于 Jan 11 2022

Western blot abreview for Anti-SAP102 antibody

Excellent
Abreviews
Abreviews
Application
Western blot
Sample
Rat Recombinant protein (HEK293)
Loading amount
50 µg
Specification
HEK293
Gel Running Conditions
Reduced Denaturing (7.5%)
Blocking step
Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 37°C
Read More
The reviewer received a reward from Abcam’s Loyalty Program in thanks for submitting this Abreview and for helping the scientific community make better-informed decisions.

Abcam user community

Verified customer

提交于 Apr 27 2009

Western blot abreview for Anti-SAP102 antibody

Good
Abreviews
Abreviews
Application
Western blot
Sample
Rat Recombinant protein (HEK 293 cell transfected homogenates)
Loading amount
25 µg
Specification
HEK 293 cell transfected homogenates
Gel Running Conditions
Reduced Denaturing
Blocking step
Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 37°C
Read More
The reviewer received a reward from Abcam’s Loyalty Program in thanks for submitting this Abreview and for helping the scientific community make better-informed decisions.

Abcam user community

Verified customer

提交于 Feb 13 2009

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