Anti-RSRC1抗体(ab106650)
Key features and details
- Rabbit polyclonal to RSRC1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
-
产品名称
Anti-RSRC1抗体 -
描述
兔多克隆抗体to RSRC1 -
宿主
Rabbit -
特异性
Two isoforms of RSRC1 are known to exist; ab106650 will detect both. -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
A 19 amino acid synthetic peptide near the C terminus of Human RSRC1 (NP_057709).
-
阳性对照
- WB: HepG2 cell lysate;
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at 4°C (stable for up to 12 months). -
存储溶液
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
-
Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab106650于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 39 kDa.
|
| 说明 |
|---|
|
WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 39 kDa. |
靶标
-
功能
Plays a role in pre-mRNA splicing. Involved in both constitutive and alternative pre-mRNA splicing. May have a role in the recognition of the 3' splice site during the second step of splicing. -
翻译后修饰
Phosphorylated. -
细胞定位
Nucleus. Nucleus speckle. Cytoplasm. Shuttles between the nucleus and cytoplasm. - Information by UniProt
-
数据库链接
- Entrez Gene: 51319 Human
- Omim: 613352 Human
- SwissProt: Q96IZ7 Human
- Unigene: 591283 Human
-
别名
- 1200013F24Rik antibody
- Arginine/serine rich coiled coil 1 antibody
- Arginine/serine-rich coiled-coil protein 1 antibody
see all
图片
-
Western blot - Anti-RSRC1 antibody (ab106650)Lane 1 : Anti-RSRC1 antibody (ab106650) at 1 µg/ml
Lane 2 : Anti-RSRC1 antibody (ab106650) at 2 µg/ml
All lanes : HepG2 cell lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 39 kDa
实验方案
数据表及文件
-
SDS download
-
Datasheet download
文献 (2)
ab106650 被引用在 2 文献中.
- Perez Y et al. RSRC1 mutation affects intellect and behaviour through aberrant splicing and transcription, downregulating IGFBP3. Brain 141:961-970 (2018). PubMed: 29522154
- McDaniel LD et al. Common variants upstream of MLF1 at 3q25 and within CPZ at 4p16 associated with neuroblastoma. PLoS Genet 13:e1006787 (2017). PubMed: 28545128