Anti-RSPH9抗体(ab224145)
Key features and details
- Rabbit polyclonal to RSPH9
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
概述
-
产品名称
Anti-RSPH9抗体
参阅全部 RSPH9 一抗 -
描述
兔多克隆抗体to RSPH9 -
宿主
Rabbit -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Cow
-
免疫原
Recombinant fragment corresponding to Human RSPH9 aa 50-200.
Database link: Q9H1X1 -
阳性对照
- IHC-P: Human fallopian tube tissue.
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 40% Glycerol (glycerin, glycerine), PBS -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab224145于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P |
1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
|
| 说明 |
|---|
|
IHC-P
1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
靶标
-
功能
Probable component of the axonemal radial spoke head. Radial spokes are regularly spaced along cilia, sperm and flagella axonemes. They consist of a thin stalk, which is attached to a subfiber of the outer doublet microtubule, and a bulbous head, which is attached to the stalk and appears to interact with the projections from the central pair of microtubules. -
疾病相关
Defects in RSPH9 are the cause of primary ciliary dyskinesia type 12 (CILD12) [MIM:612650]. CILD is an autosomal recessive disorder characterized by axonemal abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia; reduced fertility is often observed in male patients due to abnormalities of sperm tails. Half of the patients exhibit situs inversus, due to dysfunction of monocilia at the embryonic node and randomization of left-right body asymmetry. Primary ciliary dyskinesia associated with situs inversus is referred to as Kartagener syndrome. -
序列相似性
Belongs to the flagellar radial spoke RSP9 family. -
细胞定位
Cytoplasm > cytoskeleton > cilium axoneme. Radial spoke. - Information by UniProt
-
数据库链接
- Entrez Gene: 221421 Human
- Entrez Gene: 75564 Mouse
- Omim: 612648 Human
- SwissProt: Q9H1X1 Human
- SwissProt: Q9D9V4 Mouse
- Unigene: 534585 Human
- Unigene: 17993 Mouse
-
别名
- C6orf206 antibody
- Chromosome 6 open reading frame 206 antibody
- CILD12 antibody
see all
图片
-
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RSPH9 antibody (ab224145)
ab224145 staining RSPH9 of human paraffin-embedded fallopian tube and pancreas tissues by imunohistochemcial analysis shows strong cilia positivity in glandular cells (right) and no positivity in exocrine glandular cells as expected (left).
数据表及文件
-
SDS download
-
Datasheet download
文献 (0)
ab224145 尚未被引用在任何文献中。