Anti-RREB1抗体(ab64168)
Key features and details
- Rabbit polyclonal to RREB1
- Suitable for: IHC-P
- Reacts with: Mouse
- Isotype: IgG
概述
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产品名称
Anti-RREB1抗体
参阅全部 RREB1 一抗 -
描述
兔多克隆抗体to RREB1 -
宿主
Rabbit -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Mouse -
免疫原
Recombinant full length protein (Mouse)
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 0.42% Potassium phosphate, 0.87% Sodium chloride -
Concentration information loading... -
纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab64168于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P |
Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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| 说明 |
|---|
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IHC-P
Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
靶标
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功能
Transcription factor that binds specifically to the RAS-responsive elements (RRE) of gene promoters. May be involved in Ras/Raf-mediated cell differentiation by enhancing calcitonin expression. Represses the angiotensinogen gene. Negatively regulates the transcriptional activity of AR. Potentiates the transcriptional activity of NEUROD1. -
组织特异性
Expressed in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas. Not found in the brain. -
序列相似性
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 15 C2H2-type zinc fingers. -
翻译后修饰
Phosphorylated upon DNA damage, probably by ATM or ATR. -
细胞定位
Nucleus speckle. - Information by UniProt
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数据库链接
- Entrez Gene: 68750 Mouse
- SwissProt: Q3UH06 Mouse
- Unigene: 132634 Mouse
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别名
- FINB antibody
- Finger protein in nuclear bodies antibody
- Hindsight homolog antibody
see all
图片
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RREB1 antibody (ab64168)ab64168 at 10µg/ml staining RREB1 in mouse kidney by Immunohistochemistry, Formalin-fixed, paraffin-embedded tissue.
数据表及文件
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SDS download
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Datasheet download
文献 (4)
ab64168 被引用在 4 文献中.
- Dong Q et al. LncRNA SNHG4 promotes prostate cancer cell survival and resistance to enzalutamide through a let-7a/RREB1 positive feedback loop and a ceRNA network. J Exp Clin Cancer Res 42:209 (2023). PubMed: 37596700
- Pang X et al. Role of miR-145 in chronic constriction injury in rats. Exp Ther Med 12:4121-4127 (2016). PubMed: 28105140
- Kent OA et al. RREB1 repressed miR-143/145 modulates KRAS signaling through downregulation of multiple targets. Oncogene : (2012). PubMed: 22751122
- Pramanik D et al. Restitution of tumor suppressor microRNAs using a systemic nanovector inhibits pancreatic cancer growth in mice. Mol Cancer Ther 10:1470-80 (2011). IHC-P ; Mouse . PubMed: 21622730