Anti-RREB1抗体(ab113287)
Key features and details
- Rabbit polyclonal to RREB1
- Suitable for: IP
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-RREB1抗体
参阅全部 RREB1 一抗 -
描述
兔多克隆抗体to RREB1 -
宿主
Rabbit -
经测试应用
适用于: IPmore details -
种属反应性
与反应: Human
预测可用于: Chimpanzee, Rhesus monkey, Gorilla
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免疫原
Synthetic peptide corresponding to a region within amino acids 1375-1425 of Human RREB1 (NP_002946.4).
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阳性对照
- HeLa whole cell lysate (ab150035)
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7
Preservative: 0.09% Sodium azide
Constituent: 99% Tris citrate/phosphate
pH 7 to 8 -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab113287于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IP |
Use at 2-10 µg/mg of lysate.
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| 说明 |
|---|
|
IP
Use at 2-10 µg/mg of lysate. |
靶标
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功能
Transcription factor that binds specifically to the RAS-responsive elements (RRE) of gene promoters. May be involved in Ras/Raf-mediated cell differentiation by enhancing calcitonin expression. Represses the angiotensinogen gene. Negatively regulates the transcriptional activity of AR. Potentiates the transcriptional activity of NEUROD1. -
组织特异性
Expressed in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas. Not found in the brain. -
序列相似性
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 15 C2H2-type zinc fingers. -
翻译后修饰
Phosphorylated upon DNA damage, probably by ATM or ATR. -
细胞定位
Nucleus speckle. - Information by UniProt
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数据库链接
- Entrez Gene: 6239 Human
- Omim: 602209 Human
- SwissProt: Q92766 Human
- Unigene: 298248 Human
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别名
- FINB antibody
- Finger protein in nuclear bodies antibody
- Hindsight homolog antibody
see all
图片
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Immunoprecipitation - Anti-RREB1 antibody (ab113287)Detection of RREB1 in Immunoprecipitates of HeLa whole cell lysate (1 mg for IP, 20% of IP loaded) using ab113287 at 6 µg/mg lysate for IP. A Rabbit anti-RREB1 antibody which recognizes a downstream epitope was used at 1 µg/ml for subsequent Western blot detection. Lane 2 represents control IgG IP. Detection: Chemiluminescence with an exposure time of 30 seconds.
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab113287 被引用在 1 文献中.
- Ding L et al. lncRNA MELTF-AS1 facilitates osteosarcoma metastasis by modulating MMP14 expression. Mol Ther Nucleic Acids 26:787-797 (2021). PubMed: 34729248