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AB194670

Anti-RPS3A抗体- C-terminal

Anti-RPS3A antibody - C-terminal

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(3 Publications)

Mouse Polyclonal RPS3A antibody. C-terminal. Suitable for WB and reacts with Mouse, Rat, Human samples. Cited in 3 publications. Immunogen corresponding to Recombinant Fragment Protein within Human RPS3A aa 150 to C-terminus.

查看别名

FTE1, MFTL, RPS3A, Small ribosomal subunit protein eS1, 40S ribosomal protein S3a, v-fos transformation effector protein, Fte-1

4 Images
Western blot - Anti-RPS3A antibody - C-terminal (AB194670)
  • WB

Supplier Data

Western blot - Anti-RPS3A antibody - C-terminal (AB194670)

All lanes:

Western blot - Anti-RPS3A antibody - C-terminal (ab194670) at 1/500 dilution

All lanes:

HeLa cell lysate at 50 µg

Predicted band size: 30 kDa

true

Western blot - Anti-RPS3A antibody - C-terminal (AB194670)
  • WB

Supplier Data

Western blot - Anti-RPS3A antibody - C-terminal (AB194670)

All lanes:

Western blot - Anti-RPS3A antibody - C-terminal (ab194670) at 1/500 dilution

All lanes:

PC-12 cell lysate at 50 µg

Predicted band size: 16 kDa,30 kDa

Observed band size: 13 kDa

true

Western blot - Anti-RPS3A antibody - C-terminal (AB194670)
  • WB

Supplier Data

Western blot - Anti-RPS3A antibody - C-terminal (AB194670)

All lanes:

Western blot - Anti-RPS3A antibody - C-terminal (ab194670) at 1/500 dilution

All lanes:

NIH/3T3 cell lysate at 50 µg

Predicted band size: 30 kDa,33 kDa

true

Western blot - Anti-RPS3A antibody - C-terminal (AB194670)
  • WB

Supplier Data

Western blot - Anti-RPS3A antibody - C-terminal (AB194670)

All lanes:

Western blot - Anti-RPS3A antibody - C-terminal (ab194670) at 1/500 dilution

All lanes:

Raw264.7 cell lysate at 50 µg

Predicted band size: 30 kDa

true

关键信息

宿主种属

Mouse

克隆

Polyclonal

亚型

IgG

不含载体蛋白

No

反应种属

Mouse, Human, Rat

应用

WB

applications

免疫原

Recombinant Fragment Protein within Human RPS3A aa 150 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

P61247

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替代产品

Primary Antibodies

AB171742

Anti-RPS3A antibody [EPR11982(B)]

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RPS3A antibody [EPR11982(B)] (AB171742)

  • 0
  • 0
Primary Antibodies

AB226356

Anti-RPS3A antibody - N-terminal

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RPS3A antibody - N-terminal (AB226356)

  • 0
  • 0
Primary Antibodies

AB176342

Anti-RPS3A antibody [EPR11983(B)]

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RPS3A antibody [EPR11983(B)] (AB176342)

  • 0
  • 0

搭配使用产品

Primary Antibodies

AB174318

Anti-RPL10A antibody [EPR12344]

RabMAb|Recombinant

Immunocytochemistry/ Immunofluorescence - Anti-RPL10A antibody [EPR12344] (AB174318)

  • 4
  • 1
Primary Antibodies

AB196652

Anti-RPS24 antibody [EPR16017(B)]

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RPS24 antibody [EPR16017(B)] (AB196652)

  • 0
  • 0
Primary Antibodies

AB254671

Anti-RPS25 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RPS25 antibody (AB254671)

  • 0
  • 0
Primary Antibodies

AB151550

Anti-RPS10 antibody [EPR8545]

20ul selling size|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RPS10 antibody [EPR8545] (AB151550)

  • 0
  • 0
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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/1000", "WB-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/1000", "WB-species-notes": "<p></p>" }, "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/1000", "WB-species-notes": "<p></p>" }, "Cat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Cow": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Cynomolgus monkey": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Xenopus laevis": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Xenopus tropicalis": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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性能和储存信息

形式
Liquid
纯度
Whole antiserum
存储溶液
Constituents: 50% Glycerol (glycerin, glycerine)
运输条件
Blue Ice
推荐的短期储存时间
1-2 weeks
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle
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补充信息

This supplementary information is collated from multiple sources and compiled automatically.

RPS3A also known as Ribosomal Protein S3A is a component of the 40S subunit of the ribosome and has a molecular mass of approximately 29 kDa. The protein interacts directly with mRNA and transfer RNA during protein synthesis. RPS3A is expressed in various tissues including the liver spleen and muscle indicating its widespread presence where protein synthesis is highly active.
Biological function summary

Ribosomal Protein S3A plays a role in the assembly and stability of the small ribosomal subunit. It forms part of the ribosomal complex important for decoding mRNA into polypeptides. RPS3A is also involved in regulating cell growth and proliferation cell cycle progression and apoptosis linking it to cell survival and maintenance. As a ribosomal protein it associates with other ribosomal proteins and rRNA within the ribosome.

Pathways

Ribosomal Protein S3A engages in processes like the mRNA translation pathway and the ribosome biogenesis pathway. It interacts with proteins such as eukaryotic translation initiation factors ensuring the correct initiation and regulation of translation. RPS3A also associates with proteins involved in the mTOR signaling pathway which influences cell growth and metabolism by regulating protein synthesis.

Ribosomal Protein S3A has been implicated in cancer especially hepatocellular carcinoma suggesting a potential role in tumorigenesis. Abnormal expression levels of RPS3A may lead to dysregulated cell proliferation. Additionally RPS3A is associated with Diamond-Blackfan Anemia where changes in its expression could contribute to impaired ribosome function. In these contexts it may interact with proteins like RPL11 and p53 known for their roles in cellular growth regulation and genomic stability.
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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:
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靶点信息

Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed : 23636399). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed : 34516797). May play a role during erythropoiesis through regulation of transcription factor DDIT3 (By similarity).
See full target information RPS3A
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文献 (3)

Recent publications for all applications. Explore the full list and refine your search

eLife 8: PubMed31746735

2019

Receptor-specific interactome as a hub for rapid cue-induced selective translation in axons.

Applications

Unspecified application

Species

Unspecified reactive species

Max Koppers,Roberta Cagnetta,Toshiaki Shigeoka,Lucia Cs Wunderlich,Pedro Vallejo-Ramirez,Julie Qiaojin Lin,Sixian Zhao,Maximilian Ah Jakobs,Asha Dwivedy,Michael S Minett,Anaïs Bellon,Clemens F Kaminski,William A Harris,John G Flanagan,Christine E Holt

Cell 176:56-72.e15 PubMed30612743

2019

Late Endosomes Act as mRNA Translation Platforms and Sustain Mitochondria in Axons.

Applications

Unspecified application

Species

Unspecified reactive species

Jean-Michel Cioni,Julie Qiaojin Lin,Anne V Holtermann,Max Koppers,Maximilian A H Jakobs,Afnan Azizi,Benita Turner-Bridger,Toshiaki Shigeoka,Kristian Franze,William A Harris,Christine E Holt

Frontiers in physiology 8:281 PubMed28533755

2017

Proteomic Analysis of Chicken Skeletal Muscle during Embryonic Development.

Applications

WB

Species

Unspecified reactive species

Hongjia Ouyang,Zhijun Wang,Xiaolan Chen,Jiao Yu,Zhenhui Li,Qinghua Nie
View all publications
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