AB228542

Anti-RPL37 抗体

Name: RPL37抗体 (ab228542)| Abcam中文官网
Brand: Abcam Limited
SKU: AB228542
Price: 4701 CNY
Availability: InStock

Anti-RPL37 antibody

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(2 Publications)

Rabbit Polyclonal RPL37 antibody. Suitable for WB, ICC/IF and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Synthetic Peptide within Human 60S ribosomal protein L37.

查看别名

Large ribosomal subunit protein eL37, 60S ribosomal protein L37, G1.16, RPL37

3 Images

Immunocytochemistry/ Immunofluorescence - Anti-RPL37 antibody (AB228542)

ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-RPL37 antibody (AB228542)

HeLa (human epithelial cell line from cervix adenocarcinoma) cells stained for RPL37 (green) using ab228542 at 1/500 dilution in ICC/IF. Cells were fixed in 4% paraformaldehyde at RT for 15 minutes. Blue : Hoechst 33342.

Supplier Data

Western blot - Anti-RPL37 antibody (AB228542)

15% SDS-PAGE

All lanes:

Western blot - Anti-RPL37 antibody (ab228542) at 1/1000 dilution

Lane 1:

Jurkat (human T cell leukemia cell line from peripheral blood) whole cell lysate at 30 µg

Lane 2:

Raji (human Burkitt's lymphoma cell line) whole cell lysate at 30 µg

Lane 3:

NCI-H929 whole cell lysate at 30 µg

Predicted band size: 11 kDa

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Supplier Data

Western blot - Anti-RPL37 antibody (AB228542)

15% SDS-PAGE

All lanes:

Western blot - Anti-RPL37 antibody (ab228542) at 1/1000 dilution

Lane 1:

HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell lysate at 30 µg

Lane 2:

HeLa (human epithelial cell line from cervix adenocarcinoma) whole cell lysate at 30 µg

Predicted band size: 11 kDa

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关键信息

宿主种属

Rabbit

克隆

Polyclonal

亚型

IgG

不含载体蛋白

反应种属

Human

应用

WB, ICC/IF

applications

免疫原

Synthetic Peptide within Human 60S ribosomal protein L37. The exact immunogen used to generate this antibody is proprietary information.

P61927

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/100 - 1/1000", "ICCIF-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Chicken": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Chimpanzee": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Cow": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Dog": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Pig": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Xenopus laevis": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }

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性能和储存信息

形式

Liquid

纯化工艺

Affinity purification Immunogen

存储溶液

pH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: PBS, 20% Glycerol (glycerin, glycerine), 1% BSA

运输条件

Blue Ice

分装信息

Upon delivery aliquot

储存信息

Avoid freeze / thaw cycle

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补充信息

This supplementary information is collated from multiple sources and compiled automatically.

RPL37 also known as ribosomal protein L37 is a component of the 60S subunit of eukaryotic ribosomes. The protein possesses a molecular mass of approximately 11 kDa. It is expressed in various tissues throughout the body and plays a fundamental role in protein synthesis. RPL37 binds to rRNA and is involved in the assembly and structural stability of the ribosomal unit facilitating the translation process during protein expression.

Biological function summary

Ribosomal protein L37 is essential in the formation and function of ribosome complexes. It is part of the large ribosomal subunit that contributes to stabilizing the interactions between the rRNA and the mRNA-tRNA complex during translation. The precise positioning of these molecules by RPL37 helps ensure accurate decoding of mRNA into polypeptide chains highlighting its role in efficient protein production within cells.

Pathways

RPL37 is implicated in the intricate mechanics of the ribosomal biogenesis and translation pathways. Within these pathways it cooperates with other ribosomal proteins such as RPL5 and RPL10 which also form part of the large ribosomal subunit. Together they enable the step-wise assembly and function of ribosomes ultimately impacting cellular growth and proliferation through protein synthesis.

Mutations or dysregulation of RPL37 can relate to various conditions such as cancer and Diamond-Blackfan anemia. In cancer aberrant expression of RPL37 has been connected to altered ribosome function impacting cell cycle progression and growth. Additionally in Diamond-Blackfan anemia RPL37 mutations can associate with disturbed ribosomal biogenesis leading to insufficient erythrocyte production. Associated proteins such as RPL11 and RPL15 may also show altered expression in these conditions further complicating the cellular environment.

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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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靶点信息

Component of the large ribosomal subunit (PubMed : 23636399, PubMed : 32669547). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed : 23636399, PubMed : 32669547).

See full target information 60S ribosomal protein L37

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文献 (2)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in immunology 16:1580986 PubMed41019085

2025

Characterization of cancer-related fibroblasts in bladder cancer and construction of CAFs-based bladder cancer classification: insights from single-cell and multi-omics analysis.

Applications

Unspecified application

Species

Unspecified reactive species

Zhaokai Zhou,Yajun Chen,Zhan Wang,Shuai Yang,Zhengrui Li,Run Shi,Ruizhi Wang,Kui Liu,Xiaojuan Tang,Qi Li,Ran Xu

iScience 25:105366 PubMed36339258

2022

Single-cell RNA-seq transcriptomic landscape of human and mouse islets and pathological alterations of diabetes.

Applications

Unspecified application

Species

Unspecified reactive species

Kai Chen,Junqing Zhang,Youyuan Huang,Xiaodong Tian,Yinmo Yang,Aimei Dong

View all publications

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Anti-RPL37 抗体

Anti-RPL37 antibody

Immunocytochemistry/ Immunofluorescence - Anti-RPL37 antibody (AB228542)

Western blot - Anti-RPL37 antibody (AB228542)

Western blot - Anti-RPL37 antibody (AB228542)