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AB196734

Anti-RPL36抗体

Anti-RPL36 antibody

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(1 Publication)

Rabbit Polyclonal RPL36 antibody. Suitable for IHC-P, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human RPL36.

查看别名

Large ribosomal subunit protein eL36, 60S ribosomal protein L36, RPL36

2 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RPL36 antibody (AB196734)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RPL36 antibody (AB196734)

Immunohistochemical analysis of paraffin embedded human prostate carcinoma tissue labeling RPL36 using ab196734 at a 1/50 dilution. Right image treated with synthesized peptide.

Immunocytochemistry/ Immunofluorescence - Anti-RPL36 antibody (AB196734)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-RPL36 antibody (AB196734)

Immunofluorescent analysis of A549 cells labeling RPL36 using ab196734 at a 1/100 dilution. Right image treated with synthesized peptide.

关键信息

宿主种属

Rabbit

克隆

Polyclonal

亚型

IgG

不含载体蛋白

No

反应种属

Human

应用

ICC/IF, IHC-P

applications

免疫原

Synthetic Peptide within Human RPL36. The exact immunogen used to generate this antibody is proprietary information.

Q9Y3U8

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/50 - 1/100", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/100 - 1/500", "ICCIF-species-notes": "<p></p>" }, "Mouse": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }
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性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Immunogen
存储溶液
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride
运输条件
Blue Ice
推荐的短期储存时间
1-2 weeks
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle
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补充信息

This supplementary information is collated from multiple sources and compiled automatically.

RPL36 also known as Ribosomal Protein L36 is a component of the 60S subunit of the eukaryotic ribosome. This protein has a mass of approximately 12.5 kDa. RPL36 helps in the assembly of ribosomes facilitating protein synthesis in the cell. It is expressed in various tissues including the liver and brain where cell growth and division require robust protein production.
Biological function summary

RPL36 plays an essential role in the synthesis of proteins by participating in ribosome biogenesis. As part of the ribosomal complex it contributes to the formation of the large ribosomal subunit which in collaboration with the small subunit synthesizes proteins from mRNA. This function places RPL36 at the heart of cellular physiology as protein synthesis drives many cellular processes.

Pathways

RPL36 is involved in the cellular process of translation. It is part of the ribosome-mediated mechanism that translates genetic information into proteins. RPL36 associates with other ribosomal proteins like RPL10 and RPL13A within the translational machinery. Additionally it is part of the mTOR signaling pathway which regulates cell growth proliferation and survival in response to nutrient availability and other signals.

RPL36 influences conditions such as Diamond-Blackfan anemia and various cancers. In Diamond-Blackfan anemia mutations affecting ribosomal proteins like RPL36 disrupt normal erythropoiesis leading to bone marrow failure. In cancer changes in ribosomal protein expression including RPL36 may contribute to abnormal protein synthesis and tumor growth. The interplay between RPL36 and other proteins such as RPL5 and RPL11 can impact pathways critical to disease development and progression.
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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:
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靶点信息

Component of the large ribosomal subunit (PubMed : 12962325, PubMed : 23636399, PubMed : 25901680, PubMed : 25957688, PubMed : 32669547). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed : 12962325, PubMed : 23636399, PubMed : 25901680, PubMed : 25957688, PubMed : 32669547).
See full target information RPL36
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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Journal of applied physiology (Bethesda, Md. : 1985) 124:840-849 PubMed29357518

2018

Fiber type-specific analysis of AMPK isoforms in human skeletal muscle: advancement in methods via capillary nanoimmunoassay.

Applications

Unspecified application

Species

Unspecified reactive species

Irene S Tobias,Kara K Lazauskas,Jose A Arevalo,James R Bagley,Lee E Brown,Andrew J Galpin
View all publications
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