AB193164

Anti-RPL28抗体

Name: RPL28抗体 (ab193164)| Abcam中文官网
Brand: Abcam Limited
SKU: AB193164
Price: 4606 CNY
Availability: InStock

Anti-RPL28 antibody

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(2 Publications)

Rabbit Polyclonal RPL28 antibody. Suitable for ICC, IHC-P and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human RPL28.

查看别名

Large ribosomal subunit protein eL28, 60S ribosomal protein L28, RPL28

3 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RPL28 antibody (AB193164)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RPL28 antibody (AB193164)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human pancreatic tissue labelling RPL28 with ab193164 at a dilution of 1/100.

Supplier Data

Immunocytochemistry - Anti-RPL28 antibody (AB193164)

Immunocytochemistry analysis of HepG2 (Human liver hepatocellular carcinoma cell line) cells labeling RPL28 with ab193164 at dilution of 1/100.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RPL28 antibody (AB193164)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human ovarian cancer tissue labeling RPL28 with ab193164 at 1/100 dilution.

关键信息

宿主种属

Rabbit

克隆

Polyclonal

亚型

IgG

不含载体蛋白

反应种属

Human

应用

ICC, IHC-P

applications

免疫原

Recombinant Full Length Protein corresponding to Human RPL28.

P46779

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICC" : {"fullname" : "Immunocytochemistry", "shortname":"ICC"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ICC-species-checked": "testedAndGuaranteed", "ICC-species-dilution-info": "", "ICC-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/20 - 1/200", "IHCP-species-notes": "<p></p>" }, "Mouse": { "ICC-species-checked": "predicted", "ICC-species-dilution-info": "", "ICC-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "ICC-species-checked": "predicted", "ICC-species-dilution-info": "", "ICC-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Cow": { "ICC-species-checked": "predicted", "ICC-species-dilution-info": "", "ICC-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }

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性能和储存信息

形式

Liquid

纯化工艺

Affinity purification Protein G

纯化说明

>95%

存储溶液

pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)

运输条件

Blue Ice

分装信息

Upon delivery aliquot

储存信息

Avoid freeze / thaw cycle

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补充信息

This supplementary information is collated from multiple sources and compiled automatically.

The ribosomal protein L28 (RPL28) also known as 60S ribosomal protein L28 plays a mechanical role in the formation of ribosomes which are essential for protein synthesis. RPL28 forms part of the large 60S subunit of the ribosome. This protein has a molecular mass of approximately 15-17 kDa and is expressed in various tissues due to its fundamental role in cellular functions. The expression of RPL28 occurs widely but can change in response to cellular activity related to protein production needs.

Biological function summary

RPL28 participates in the assembly and function of ribosomes within the cell. It acts as a structural component of the ribosomal large subunit and therefore helps in the synthesis of proteins by translating mRNA. As part of the ribosomal complex RPL28 ensures the proper alignment of rRNA and tRNA during protein assembly. Its function is integral to the ribosome's role in facilitating correct translation steps needed for cellular protein production.

Pathways

RPL28 has important roles in the protein synthesis (translation) and ribosome biogenesis pathways. It interacts with other ribosomal proteins and factors involved in these pathways. RPL28 coordinates with proteins such as RPL5 and RPL11 which are also involved in the assembly of the large ribosomal subunit and ensure effective translation and synthesis of proteins required by the cell.

Mutations or alterations in RPL28 expression have connections to disorders of ribosome dysfunction known as ribosomopathies. Such conditions may include Diamond-Blackfan Anemia where ribosomal biogenesis is impaired possibly involving other proteins like RPL5. Deficiencies in RPL28 or associated proteins can lead to abnormal ribosome assembly affecting protein synthesis and contributing to disease symptoms.

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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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靶点信息

Component of the large ribosomal subunit (PubMed : 12962325, PubMed : 23636399, PubMed : 32669547). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed : 12962325, PubMed : 23636399, PubMed : 32669547).

See full target information RPL28

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文献 (2)

Recent publications for all applications. Explore the full list and refine your search

Metabolites 15: PubMed40710572

2025

Aerobic Exercise Delays Age-Related Sarcopenia in Mice via Alleviating Imbalance in Mitochondrial Quality Control.

Applications

Unspecified application

Species

Unspecified reactive species

Danlin Zhu,Lian Wang,Haoyang Gao,Ze Wang,Ke Li,Xiaotong Ma,Linlin Zhao,Weihua Xiao

Cell reports 41:111571 PubMed36323262

2022

Nuclear stabilization of p53 requires a functional nucleolar surveillance pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Katherine M Hannan,Priscilla Soo,Mei S Wong,Justine K Lee,Nadine Hein,Perlita Poh,Kira D Wysoke,Tobias D Williams,Christian Montellese,Lorey K Smith,Sheren J Al-Obaidi,Lorena Núñez-Villacís,Megan Pavy,Jin-Shu He,Kate M Parsons,Karagh E Loring,Tess Morrison,Jeannine Diesch,Gaetan Burgio,Rita Ferreira,Zhi-Ping Feng,Cathryn M Gould,Piyush B Madhamshettiwar,Johan Flygare,Thomas J Gonda,Kaylene J Simpson,Ulrike Kutay,Richard B Pearson,Christoph Engel,Nicholas J Watkins,Ross D Hannan,Amee J George

View all publications

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Anti-RPL28抗体

Anti-RPL28 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RPL28 antibody (AB193164)

Immunocytochemistry - Anti-RPL28 antibody (AB193164)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RPL28 antibody (AB193164)

关键信息

宿主种属

克隆

亚型

不含载体蛋白

反应种属

应用

免疫原

反应性数据

性能和储存信息

形式

纯化工艺

纯化说明

存储溶液

运输条件

推荐的短期储存时间

推荐的短期储存条件

推荐的长期储存条件

分装信息

储存信息

补充信息

Biological function summary

Pathways

产品实验方案

靶点信息

文献 (2)

Abcam Product Promise

Anti-RPL28抗体

Anti-RPL28 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RPL28 antibody (AB193164)

Immunocytochemistry - Anti-RPL28 antibody (AB193164)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RPL28 antibody (AB193164)

关键信息

宿主种属

克隆

亚型

不含载体蛋白

反应种属

应用

免疫原

替代产品

Primary Antibodies

Primary Antibodies

搭配使用产品

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

反应性数据

性能和储存信息

形式

纯化工艺

纯化说明

存储溶液

运输条件

推荐的短期储存时间

推荐的短期储存条件

推荐的长期储存条件

分装信息

储存信息

补充信息

Biological function summary

Pathways

产品实验方案

靶点信息

文献 (2)

Abcam Product Promise