重组Anti-RPC39抗体[EPR13200] (ab180501)
![Western blot - Anti-RPC39 antibody [EPR13200] (ab180501)](https://www.abcam.cn/ps/products/180/ab180501/Images/ab180501-211162-ab180501.jpg "Western blot - Anti-RPC39 antibody [EPR13200] (ab180501)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR13200] to RPC39
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
概述
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产品名称
Anti-RPC39抗体[EPR13200]
参阅全部 RPC39 一抗 -
描述
兔单克隆抗体[EPR13200] to RPC39 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat
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免疫原
Recombinant fragment. This information is proprietary to Abcam and/or its suppliers.
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阳性对照
- BxPC-3, HeLa, A431 and HepG2 lysates.
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常规说明
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
Preservative: 0.01% Sodium azide
Constituents: 40% Glycerol (glycerin, glycerine), 59% PBS, 0.05% BSA -
Concentration information loading... -
纯度
Protein A purified -
克隆
单克隆 -
克隆编号
EPR13200 -
同种型
IgG -
研究领域
相关产品
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Alternative Versions
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Isotype control
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Positive Controls
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Recombinant Protein
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Related Products
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab180501于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/1000 - 1/10000. Detects a band of approximately 36 kDa (predicted molecular weight: 36 kDa).
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| 说明 |
|---|
|
WB
1/1000 - 1/10000. Detects a band of approximately 36 kDa (predicted molecular weight: 36 kDa). |
靶标
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功能
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct RNA Pol III binding to the TFIIIB-DNA complex. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway. -
序列相似性
Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. -
细胞定位
Nucleus. - Information by UniProt
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数据库链接
- Entrez Gene: 10621 Human
- Entrez Gene: 70408 Mouse
- Entrez Gene: 311487 Rat
- SwissProt: Q9H1D9 Human
- SwissProt: Q921X6 Mouse
- Unigene: 472227 Human
- Unigene: 389351 Mouse
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别名
- DNA directed RNA polymerase III 39 kDa polypeptide antibody
- DNA directed RNA polymerase III 39 kDa polypeptide F antibody
- DNA directed RNA polymerase III subunit F antibody
see all
图片
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Western blot - Anti-RPC39 antibody [EPR13200] (ab180501)All lanes : Anti-RPC39 antibody [EPR13200] (ab180501) at 1/1000 dilution
Lane 1 : BxPC-3 lysate
Lane 2 : Hela lysate
Lane 3 : A431 lysate
Lane 4 : HepG2 lysate
Lysates/proteins at 20 µg per lane.
Secondary
All lanes : Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution
Predicted band size: 36 kDa
Additional bands at: 36 kDa. We are unsure as to the identity of these extra bands. -
![Anti-RPC39 antibody [EPR13200] (ab180501)](https://www.abcam.cn/ps/products/180/ab180501/Images/ab180501-2-benefits-of-recombinant-antibodies.png)
Anti-RPC39 antibody [EPR13200] (ab180501)
数据表及文件
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SDS download
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Datasheet download
Certificate of Compliance
文献 (0)
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