重组Anti-RNF36抗体[EPR4755] (ab111943)
![Western blot - Anti-RNF36 antibody [EPR4755] (ab111943)](https://www.abcam.cn/ps/products/111/ab111943/Images/ab111943-125197-anti-rnf36-antibody-epr4755-western-blot.jpg "Western blot - Anti-RNF36 antibody [EPR4755] (ab111943)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR4755] to RNF36
- Suitable for: WB
- Reacts with: Mouse, Human
Related conjugates and formulations
概述
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产品名称
Anti-RNF36抗体[EPR4755]
参阅全部 RNF36 一抗 -
描述
兔单克隆抗体[EPR4755] to RNF36 -
宿主
Rabbit -
特异性
ab111943 detects at least 4 isoforms. -
经测试应用
适用于: WBmore details
不适用于: Flow Cyt,ICC/IF,IHC-P or IP -
种属反应性
与反应: Mouse, Human
预测可用于: Rat
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免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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阳性对照
- Human testis and Neuro-2a cell lysates.
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常规说明
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
存储溶液
pH: 7.20
Preservative: 0.05% Sodium azide
Constituents: 0.1% BSA, 40% Glycerol (glycerin, glycerine), 9.85% Tris glycine, 50% Tissue culture supernatant -
Concentration information loading... -
纯度
Protein A purified -
克隆
单克隆 -
克隆编号
EPR4755 -
同种型
IgG -
研究领域
相关产品
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Alternative Versions
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab111943于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/1000 - 1/10000. Detects a band of approximately 29-54 kDa (predicted molecular weight: 57 kDa).
|
| 说明 |
|---|
|
WB
1/1000 - 1/10000. Detects a band of approximately 29-54 kDa (predicted molecular weight: 57 kDa). |
应用说明
Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
靶标
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功能
May play a role in apoptosis. -
序列相似性
Belongs to the TRIM/RBCC family.
Contains 1 B30.2/SPRY domain.
Contains 1 RING-type zinc finger. -
翻译后修饰
Phosphorylated. Phosphorylation is necessary for nuclear localization. -
细胞定位
Nucleus speckle. - Information by UniProt
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数据库链接
- Entrez Gene: 140691 Human
- Entrez Gene: 70928 Mouse
- Entrez Gene: 311373 Rat
- SwissProt: Q86WT6 Human
- SwissProt: Q80X56 Mouse
- SwissProt: Q5BK82 Rat
- Unigene: 489254 Human
- Unigene: 379188 Mouse
see all -
别名
- E3 ubiquitin protein ligase TRIM69 antibody
- HSD34 antibody
- RFP like domain containing protein trimless antibody
see all
图片
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Western blot - Anti-RNF36 antibody [EPR4755] (ab111943)Anti-RNF36 antibody [EPR4755] (ab111943) at 1/1000 dilution + Human testis lysate at 10 µg
Predicted band size: 57 kDa -
![Western blot - Anti-RNF36 antibody [EPR4755] (ab111943)](https://www.abcam.cn/ps/products/111/ab111943/Images/ab111943-125196-anti-rnf36-antibody-epr4755-western-blot.jpg)
Western blot - Anti-RNF36 antibody [EPR4755] (ab111943)Anti-RNF36 antibody [EPR4755] (ab111943) at 1/1000 dilution + Neuro-2a cell lysate at 10 µg
Predicted band size: 57 kDa -
![Anti-RNF36 antibody [EPR4755] (ab111943)](https://www.abcam.cn/ps/products/111/ab111943/Images/ab111943-3-benefits-of-recombinant-antibodies.png)
Anti-RNF36 antibody [EPR4755] (ab111943)
数据表及文件
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SDS download
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Datasheet download
文献 (4)
ab111943 被引用在 4 文献中.
- Jia Y et al. Tripartite motif containing 69 elicits ERK2-dependent EYA4 turnover to impart pancreatic tumorigenesis. J Cancer 14:200-218 (2023). PubMed: 36741265
- Rihn SJ et al. TRIM69 Inhibits Vesicular Stomatitis Indiana Virus. J Virol 93:N/A (2019). PubMed: 31375575
- Rong X et al. TRIM69 inhibits cataractogenesis by negatively regulating p53. Redox Biol 22:101157 (2019). PubMed: 30844644
- Wang K et al. Interferon-stimulated TRIM69 interrupts dengue virus replication by ubiquitinating viral nonstructural protein 3. PLoS Pathog 14:e1007287 (2018). PubMed: 30142214