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AB5131

Anti-RNA polymerase II CTD repeat YSPTSPS (phospho S5) 抗体

Anti-RNA polymerase II CTD repeat YSPTSPS (phospho S5) antibody

4

(48 Reviews)

|

(444 Publications)

Anti-RNA polymerase II CTD repeat YSPTSPS (phospho S5) antibody (ab5131) is a rabbit polyclonal antibody for Western Blot, IP, IHC, ICC/IF, ELISA, ChIP in Arabidopsis, C.elegans, Drosophila, Human, Mouse, Rat, S.cerevisiae, S.pombe, Xenopus, Zebrafish.

- Over 440 publications
- Trusted since 2005

查看别名

POLR2, POLR2A, DNA-directed RNA polymerase II subunit RPB1, RNA polymerase II subunit B1, 3'-5' exoribonuclease, DNA-directed RNA polymerase II subunit A, DNA-directed RNA polymerase III largest subunit, RNA-directed RNA polymerase II subunit RPB1

7 Images
ChIP - Anti-RNA polymerase II CTD repeat YSPTSPS (phospho S5) antibody (AB5131)
  • ChIP

Unknown

ChIP - Anti-RNA polymerase II CTD repeat YSPTSPS (phospho S5) antibody (AB5131)

Chromatin was prepared from U-2 OS (Human bone osteosarcoma epithelial cell line) cells according to the Abcam X-ChIP protocol.

Cells were fixed with formaldehyde for 10 minutes. The ChIP was performed with 25 μg of chromatin, 2 μg of ab5131 (blue), and 20 μl of Protein A/G sepharose beads. No antibody was added to the beads control (yellow). The immunoprecipitated DNA was quantified on the inactive AFM and F8 promoters, the GAPDH promoter (active) and over the y-Actin gene (active).

Schematic diagram of the y-Actin gene is shown on the top of the figure. Black boxes represent exons and thin lines represent introns. PCR products are depicted as bars under the gene.

ChIP - Anti-RNA polymerase II CTD repeat YSPTSPS (phospho S5) antibody (AB5131)
  • ChIP

PubMed

ChIP - Anti-RNA polymerase II CTD repeat YSPTSPS (phospho S5) antibody (AB5131)

Chromatin from cultured cells, mouse PVN punches (individual pools formed from groups of 3) or whole hypothalami dissected from fresh brains were cross linked, disrupted by sonification and purified.

The binding of Suz12 to wingless (Wnt1), a beta-catenin dependent developmental regulator and to the RNA polymerase II promoter (RNAPII), a housekeeping gene, served as positive and negative controls, respectively, in these experiments.

Murgatroyd et al PLoS One. 2014 Mar 5;9(3):e90277. doi: 10.1371/journal.pone.0090277. eCollection 2014. Fig S2. Reproduced under the Creative Commons license http://creativecommons.org/licenses/by/4.0/

Western blot - Anti-RNA polymerase II CTD repeat YSPTSPS (phospho S5) antibody (AB5131)
  • WB

Project5649****

Western blot - Anti-RNA polymerase II CTD repeat YSPTSPS (phospho S5) antibody (AB5131)

All lanes:

Western blot - Anti-RNA polymerase II CTD repeat YSPTSPS (phospho S5) antibody (ab5131) at 1 µg/mL

Lanes 1, 5 and 7:

HeLa (Human epithelial carcinoma cell line) Nuclear Lysate at 20 µg

Lanes 2, 6 and 8:

S.cerevisiae (Y190) Whole Cell Lysate at 20 µg

Lane 3:

HeLa (Human epithelial carcinoma cell line) Nuclear Lysate at 20 µg with <em>S. cerevisiae</em> RNA polymerase II CTD repeat YSPTSPS peptide (<a href='/products/unavailable/s-cerevisiae-rna-polymerase-ii-ctd-repeat-ysptsps-peptide-ab12795'>ab12795</a>)

Lane 4:

S.cerevisiae (Y190) Whole Cell Lysate at 20 µg with <em>S. cerevisiae</em> RNA polymerase II CTD repeat YSPTSPS peptide (<a href='/products/unavailable/s-cerevisiae-rna-polymerase-ii-ctd-repeat-ysptsps-peptide-ab12795'>ab12795</a>)

Secondary

All lanes:

Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution

Predicted band size: 217 kDa

true

Exposure time: 30s

Immunocytochemistry/ Immunofluorescence - Anti-RNA polymerase II CTD repeat YSPTSPS (phospho S5) antibody (AB5131)
  • ICC/IF

Lab

Immunocytochemistry/ Immunofluorescence - Anti-RNA polymerase II CTD repeat YSPTSPS (phospho S5) antibody (AB5131)

ab5131 staining RNA polymerase II CTD repeat YSPTSPS (phospho S5) in HeLa cells. The cells were fixed with 100% methanol (5 min), permeabilized with 0.1% PBS-Triton X-100 for 5 minutes and then blocked with 1% BSA/10% normal goat serum/0.3M glycine in 0.1% PBS-Tween for 1h. The cells were then incubated overnight at 4°C with ab5131 at 1µg/ml and ab7291, Mouse monoclonal [DM1A] to alpha Tubulin - Loading Control. Cells were then incubated with ab150081, Goat polyclonal Secondary Antibody to Rabbit IgG - H&L (Alexa Fluor® 488), pre-adsorbed at 1/1000 dilution (shown in green) and ab150120, Goat polyclonal Secondary Antibody to Mouse IgG - H&L (Alexa Fluor® 594), pre-adsorbed at 1/1000 dilution (shown in pseudocolour red). Nuclear DNA was labelled with DAPI (shown in blue).

Also suitable in cells fixed with 4% paraformaldehyde (10 min).

Image was acquired with a high-content analyser (Operetta CLS, Perkin Elmer) and a maximum intensity projection of confocal sections is shown.

Immunocytochemistry/ Immunofluorescence - Anti-RNA polymerase II CTD repeat YSPTSPS (phospho S5) antibody (AB5131)
  • ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-RNA polymerase II CTD repeat YSPTSPS (phospho S5) antibody (AB5131)

ICC/IF image of ab5131 stained HeLa(Human epithelial cell line from cervix adenocarcinoma) cells.

The cells were fixed in methanol for 5 minutes, permabilized in TBS-T for 20 minutes and incubated with the antibody (ab5131, 1 μg/ml) for 1 hour at room temperature. 1% BSA / 10% normal goat serum / 0.3M glycine was used to quench auto-fluorescence and block non-specific protein-protein interactions.

The secondary antibody (green) was Alexa Fluor® 488 goat anti-rabbit IgG (H+L) used at a 1/1000 dilution for 1 hour. Alexa Fluor® 594 WGA was used to label plasma membranes (red). DAPI was used to stain the cell nuclei (blue).

Western blot - Anti-RNA polymerase II CTD repeat YSPTSPS (phospho S5) antibody (AB5131)
  • WB

AbReview40285****

Western blot - Anti-RNA polymerase II CTD repeat YSPTSPS (phospho S5) antibody (AB5131)

All lanes:

Western blot - Anti-RNA polymerase II CTD repeat YSPTSPS (phospho S5) antibody (ab5131) at 1/5000 dilution

Lane 1:

Xenopus laevis whole tissue lysate treated with DMSO for 24 hours

Lane 2:

Xenopus laevis whole tissue lysate treated with CDK inhibitor for 24 hours

Secondary

All lanes:

HRP-conjugated goat anti-rabbit IgG polyclonal at 1/10000 dilution

Predicted band size: 217 kDa

Observed band size: 240 kDa

true

Exposure time: 1min

This image is courtesy of an anonymous Abreview

Western blot - Anti-RNA polymerase II CTD repeat YSPTSPS (phospho S5) antibody (AB5131)
  • WB

Unknown

Western blot - Anti-RNA polymerase II CTD repeat YSPTSPS (phospho S5) antibody (AB5131)

Lanes 1, 3 and 4:

Western blot - Anti-RNA polymerase II CTD repeat YSPTSPS (phospho S5) antibody (ab5131) at 1/500 dilution

Lane 2:

Western blot - Anti-RNA polymerase II CTD repeat YSPTSPS (phospho S5) antibody (ab5131) at 1/2000 dilution

Lanes 1 - 3:

HeLa nuclear extract at 20 µg

Lane 4:

HeLa nuclear extract at 20 µg with <em>S. cerevisiae</em> RNA polymerase II CTD repeat YSPTSPS peptide (<a href='/products/unavailable/s-cerevisiae-rna-polymerase-ii-ctd-repeat-ysptsps-peptide-ab12795'>ab12795</a>)

Secondary

All lanes:

Western blot - Goat Anti-Rabbit IgG H&L (HRP) (<a href='/products/secondary-antibodies/goat-rabbit-igg-h-l-hrp-ab6721'>ab6721</a>) at 1/5000 dilution

Predicted band size: 217 kDa

Observed band size: 250 kDa

false

Exposure time: 30s

关键信息

宿主种属

Rabbit

克隆

Polyclonal

亚型

IgG

不含载体蛋白

No

反应种属

Human, Zebrafish, Mouse, Saccharomyces cerevisiae, Arabidopsis thaliana, Schizosaccharomyces pombe, Xenopus laevis, Rat, Caenorhabditis elegans, Drosophila melanogaster

应用

IHC-Fr, ELISA, IHC-P, ICC/IF, IP, WB, ChIP, IHC - Wmt

applications

免疫原

This product was produced with the following immunogens:

The exact immunogen used to generate this antibody is proprietary information.

The exact immunogen used to generate this antibody is proprietary information.

The exact immunogen used to generate this antibody is proprietary information.

特异性

This antibody recognises the phosphorylated serine found in the amino acid 5 position of the C-terminal domain repeat YSPTSPS of RNA polymerase II. From Jan 2024, QC testing of replenishment batches of this polyclonal changed. All tested and expected application and reactive species combinations are still covered by our Abcam product promise. However, we no longer test all applications. For more information on a specific batch, please contact our Scientific Support who will be happy to help.

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反应性数据

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"guaranteed", "WB-species-dilution-info": "1/1000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "1 µg/mL", "ICCIF-species-notes": "<p></p>", "IHCWmt-species-checked": "guaranteed", "IHCWmt-species-dilution-info": "", "IHCWmt-species-notes": "<p></p>", "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "<p></p>" }, "Drosophila melanogaster": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "<p></p>", "ChIP-species-checked": "guaranteed", "ChIP-species-dilution-info": "2 µg for 25 µg chromatin", "ChIP-species-notes": "<p></p>", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p></p>", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "1/1000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "1 µg/mL", "ICCIF-species-notes": "<p></p>", "IHCWmt-species-checked": "guaranteed", "IHCWmt-species-dilution-info": "", "IHCWmt-species-notes": "<p></p>", "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "<p></p>" }, "Saccharomyces cerevisiae": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "<p></p>", "ChIP-species-checked": "guaranteed", "ChIP-species-dilution-info": "2 µg for 25 µg chromatin", "ChIP-species-notes": "<p></p>", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p></p>", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "1/1000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "1 µg/mL", "ICCIF-species-notes": "<p></p>", "IHCWmt-species-checked": "guaranteed", "IHCWmt-species-dilution-info": "", "IHCWmt-species-notes": "<p></p>", "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "<p></p>" }, "Schizosaccharomyces pombe": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "<p></p>", "ChIP-species-checked": "guaranteed", "ChIP-species-dilution-info": "2 µg for 25 µg chromatin", "ChIP-species-notes": "<p></p>", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p></p>", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "1/1000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", 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"IHCWmt-species-checked": "guaranteed", "IHCWmt-species-dilution-info": "", "IHCWmt-species-notes": "<p></p>", "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "<p></p>" }, "Zebrafish": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "<p></p>", "ChIP-species-checked": "guaranteed", "ChIP-species-dilution-info": "2 µg for 25 µg chromatin", "ChIP-species-notes": "<p></p>", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p></p>", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "1/1000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "1 µg/mL", "ICCIF-species-notes": "<p></p>", "IHCWmt-species-checked": "guaranteed", "IHCWmt-species-dilution-info": "", "IHCWmt-species-notes": "<p></p>", "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "<p></p>" } } }
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您是否考虑以下替代产品？

AB193467

Anti-RNA polymerase II CTD repeat YSPTSPS (phospho S5) antibody [EPR19015]

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为什么推荐这个？

为向您提供最高品质的产品，我们在不断升级产品范围。我们选择了这个替代产品供您参考，因为它提供了更好的性能，更容易和更方便的使用，或交期更快。

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产品详情

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性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Immunogen
存储溶液
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: 98.98% PBS, 1% BSA
运输条件
Blue Ice
推荐的短期储存时间
1-2 weeks
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle
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补充信息

This supplementary information is collated from multiple sources and compiled automatically.

RNA polymerase II CTD repeat YSPTSPS also known as the C-terminal domain of RNA polymerase II is a critical component of the RNA polymerase II enzyme commonly referred to as pol II. This domain is characterized by the repetitive sequence YSPTSPS which plays a significant role in the regulation of transcription. The mass of RNA polymerase II including its CTD varies but is essential for its function in gene expression. RNA polymerase II with the CTD is expressed in the nucleus of eukaryotic cells where it orchestrates the transcription of DNA into mRNA.
Biological function summary

RNA polymerase II CTD repeat YSPTSPS is essential for the transcription progression from initiation to termination. It is part of the large RNA polymerase II complex interacting with various transcription factors and enzymes necessary for RNA processing. The phosphorylation state of the CTD particularly on serine residues regulates interactions with splicing machinery and other RNA processing factors. This modulation ensures the coupling between transcription and RNA processing events controlling mRNA synthesis and maturation.

Pathways

RNA polymerase II CTD repeat YSPTSPS is important in the mRNA synthesis pathway specifically in transcriptional regulation and processing of nascent RNA transcripts. It interacts with proteins such as the transcription factors TFIIH and TFIIB which aid in promoter recognition and open complex formation. The CTD's dynamic phosphorylation pattern allows integration into multiple cellular pathways most importantly connecting transcription with RNA splicing and transport pathways.

Abnormal function or mutations in RNA polymerase II CTD repeat YSPTSPS associate with diseases such as transcription-related syndromes and certain cancers. Deficient CTD phosphorylation can lead to improper mRNA processing resulting in neural developmental disorders. Additionally its interaction with proteins like CDK7 which phosphorylates the CTD links it to tumors where transcriptional dysregulation is a hallmark. Understanding the CTD's role in these diseases provides insight into therapeutic targets and strategies for intervention.
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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:
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靶点信息

Catalytic core component of RNA polymerase II (Pol II), a DNA-dependent RNA polymerase which synthesizes mRNA precursors and many functional non-coding RNAs using the four ribonucleoside triphosphates as substrates (By similarity) (PubMed : 23748380, PubMed : 27193682, PubMed : 30190596, PubMed : 9852112). Pol II-mediated transcription cycle proceeds through transcription initiation, transcription elongation and transcription termination stages. During transcription initiation, Pol II pre-initiation complex (PIC) is recruited to DNA promoters, with focused-type promoters containing either the initiator (Inr) element, or the TATA-box found in cell-type specific genes and dispersed-type promoters that often contain hypomethylated CpG islands usually found in housekeeping genes. Once the polymerase has escaped from the promoter it enters the elongation phase during which RNA is actively polymerized, based on complementarity with the template DNA strand. Transcription termination involves the release of the RNA transcript and polymerase from the DNA (By similarity) (PubMed : 23748380, PubMed : 27193682, PubMed : 28108474, PubMed : 30190596, PubMed : 9852112). Forms Pol II active center together with the second largest subunit POLR2B/RPB2. Appends one nucleotide at a time to the 3' end of the nascent RNA, with POLR2A/RPB1 most likely contributing a Mg(2+)-coordinating DxDGD motif, and POLR2B/RPB2 participating in the coordination of a second Mg(2+) ion and providing lysine residues believed to facilitate Watson-Crick base pairing between the incoming nucleotide and template base. Typically, Mg(2+) ions direct a 5' nucleoside triphosphate to form a phosphodiester bond with the 3' hydroxyl of the preceding nucleotide of the nascent RNA, with the elimination of pyrophosphate. The reversible pyrophosphorolysis can occur at high pyrophosphate concentrations (By similarity) (PubMed : 30190596, PubMed : 8381534, PubMed : 9852112). Can proofread the nascent RNA transcript by means of a 3' -> 5' exonuclease activity. If a ribonucleotide is mis-incorporated, backtracks along the template DNA and cleaves the phosphodiester bond releasing the mis-incorporated 5'-ribonucleotide (By similarity) (PubMed : 8381534). Through its unique C-terminal domain (CTD, 52 heptapeptide tandem repeats) serves as a platform for assembly of factors that regulate transcription initiation, elongation and termination. CTD phosphorylation on Ser-5 mediates Pol II promoter escape, whereas phosphorylation on Ser-2 is required for Pol II pause release during transcription elongation and further pre-mRNA processing. Additionally, the regulation of gene expression levels depends on the balance between methylation and acetylation levels of the CTD-lysines. Initiation or early elongation steps of transcription of growth-factor-induced immediate early genes are regulated by the acetylation status of the CTD. Methylation and dimethylation have a repressive effect on target genes expression. Cooperates with mRNA splicing machinery in co-transcriptional 5'-end capping and co-transcriptional splicing of pre-mRNA (By similarity) (PubMed : 24207025, PubMed : 26124092).. RNA-dependent RNA polymerase that catalyzes the extension of a non-coding RNA (ncRNA) at the 3'-end using the four ribonucleoside triphosphates as substrates. An internal ncRNA sequence near the 3'-end serves as a template in a single-round Pol II-mediated RNA polymerization reaction. May decrease the stability of ncRNAs that repress Pol II-mediated gene transcription.. (Microbial infection) Acts as an RNA-dependent RNA polymerase when associated with small delta antigen of Hepatitis delta virus, acting both as a replicase and transcriptase for the viral RNA circular genome.
See full target information POLR2A phospho S5
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文献 (444)

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EWSR1::ATF1 Orchestrates the Clear Cell Sarcoma Transcriptome in Human Tumors and a Mouse Genetic Model.

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Dissecting transcription of the 8q24-MYC locus in prostate cancer recognizes the equilibration between androgen receptor direct and indirect dual-functions.

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Species

Unspecified reactive species

Ju Guo,Zhao Wei,Tianwei Jia,Liyang Wang,Nuosu Nama,Jiaqian Liang,Xinghua Liao,Xiaming Liu,Yanfei Gao,Xiaoqiang Liu,Keshan Wang,Bin Fu,Shaoyong Shawn Chen

Cell reports 42:112505 PubMed37182209

2023

Regulatory architecture of housekeeping genes is driven by promoter assemblies.

Applications

Unspecified application

Species

Unspecified reactive species

Marion Dejosez,Alessandra Dall'Agnese,Mahesh Ramamoorthy,Jesse Platt,Xing Yin,Megan Hogan,Ran Brosh,Abraham S Weintraub,Denes Hnisz,Brian J Abraham,Richard A Young,Thomas P Zwaka

Molecular therapy. Nucleic acids 32:637-649 PubMed37207130

2023

Streamlined DNA-encoded small molecule library screening and validation for the discovery of novel chemotypes targeting BET proteins.

Applications

Unspecified application

Species

Unspecified reactive species

Seoyeon Jeong,Hwa-Ryeon Kim,June-Ha Shin,Min-Hee Son,In-Hyun Lee,Jae-Seok Roe

Cell death & disease 14:245 PubMed37024465

2023

CMTR1 promotes colorectal cancer cell growth and immune evasion by transcriptionally regulating STAT3.

Applications

Unspecified application

Species

Unspecified reactive species

A-Bin You,Hu Yang,Chun-Ping Lai,Wen Lei,Lu Yang,Jia-Lin Lin,Shun-Cui Liu,Nan Ding,Feng Ye

Cell reports 42:112341 PubMed37018072

2023

PYHIN protein IFI207 regulates cytokine transcription and IRF7 and contributes to the establishment of K. pneumoniae infection.

Applications

Unspecified application

Species

Unspecified reactive species

Marcin Baran,Claudia Feriotti,Aoife McGinley,Simon R Carlile,Zhaozhao Jiang,Ricardo Calderon-Gonzalez,Amy Dumigan,Joana Sá-Pessoa,Caroline E Sutton,Jay Kearney,Rachel M McLoughlin,Kingston H G Mills,Katherine A Fitzgerald,Jose A Bengeochea,Andrew G Bowie

Nucleic acids research 51:4341-4362 PubMed36928661

2023

Excessive transcription-replication conflicts are a vulnerability of BRCA1-mutant cancers.

Applications

Unspecified application

Species

Unspecified reactive species

Parasvi S Patel,Arash Algouneh,Rehna Krishnan,John J Reynolds,Kevin C J Nixon,Jun Hao,Jihoon Lee,Yue Feng,Chehronai Fozil,Mia Stanic,Talya Yerlici,Peiran Su,Fraser Soares,Elisabeth Liedtke,Gil Prive,Gary D Baider,Miquel Angel Pujana,Karim Mekhail,Housheng Hansen He,Anne Hakem,Grant S Stewart,Razqallah Hakem

Genome research 33:332-345 PubMed36927987

2023

The impact of SWI/SNF and NuRD inactivation on gene expression is tightly coupled with levels of RNA polymerase II occupancy at promoters.

Applications

Unspecified application

Species

Unspecified reactive species

Sachin Pundhir,Jinyu Su,Marta Tapia,Anne Meldgaard Hansen,James Seymour Haile,Klaus Hansen,Bo Torben Porse

Cell reports 42:112257 PubMed36930642

2023

Chromatin profiling identifies transcriptional readthrough as a conserved mechanism for piRNA biogenesis in mosquitoes.

Applications

Unspecified application

Species

Unspecified reactive species

Jieqiong Qu,Valerie Betting,Ruben van Iterson,Florence M Kwaschik,Ronald P van Rij

Nature plants 9:460-472 PubMed36879017

2023

A gene silencing screen uncovers diverse tools for targeted gene repression in Arabidopsis.

Applications

Unspecified application

Species

Unspecified reactive species

Ming Wang,Zhenhui Zhong,Javier Gallego-Bartolomé,Zheng Li,Suhua Feng,Hsuan Yu Kuo,Ryan L Kan,Hoiyan Lam,John Curtis Richey,Linli Tang,Jessica Zhou,Mukun Liu,Yasaman Jami-Alahmadi,James Wohlschlegel,Steven E Jacobsen
View all publications
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