重组Anti-RGS22抗体[EPR7005] (ab131048)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR7005] to RGS22
- Suitable for: WB
- Reacts with: Rat
Related conjugates and formulations
概述
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产品名称
Anti-RGS22抗体[EPR7005]
参阅全部 RGS22 一抗 -
描述
兔单克隆抗体[EPR7005] to RGS22 -
宿主
Rabbit -
经测试应用
适用于: WBmore details
不适用于: IHC-P or IP -
种属反应性
与反应: Rat
预测可用于: Mouse, Human -
免疫原
Synthetic peptide within Human RGS22 aa 200-300. The exact sequence is proprietary.
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阳性对照
- Rat testis lysate
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常规说明
This antibody was developed as part of a collaboration with the lab of Damian Romero at the University of Mississippi Medical Center.
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
解离常数(KD)
KD = 1.30 x 10 -10 M Learn more about KD -
存储溶液
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading...
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纯度
Protein A purified -
克隆
单克隆 -
克隆编号
EPR7005 -
同种型
IgG -
研究领域
相关产品
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Alternative Versions
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab131048于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/1000 - 1/10000. Detects a band of approximately 150 kDa (predicted molecular weight: 147 kDa).
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说明 |
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WB
1/1000 - 1/10000. Detects a band of approximately 150 kDa (predicted molecular weight: 147 kDa). |
靶标
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功能
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. -
序列相似性
Contains 2 RGS domains. - Information by UniProt
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数据库链接
- Entrez Gene: 26166 Human
- Entrez Gene: 626596 Mouse
- Entrez Gene: 500853 Rat
- SwissProt: Q8NE09 Human
- SwissProt: G3UYX5 Mouse
- Unigene: 120021 Human
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别名
- FLJ40080 antibody
- FLJ75004 antibody
- MGC102908 antibody
see all
图片
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Anti-RGS22 antibody [EPR7005] (ab131048) at 1/1000 dilution + Rat testis lysate at 10 µg
Secondary
HRP labelled goat anti-rabbit at 1/2000 dilution
Predicted band size: 147 kDa
Observed band size: 150 kDa why is the actual band size different from the predicted?
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab131048 被引用在 1 文献中.
- Cao SJ et al. Suppressive effect of YY1-mediated RGS22 regulation on the proliferation, migration and invasion of pancreatic ductal adenocarcinoma. Oncol Lett 24:457 (2022). PubMed: 36380881