Anti-Respiratory Syncytial Virus抗体[2F7] (ab43812)
![Immunocytochemistry/ Immunofluorescence - Anti-Respiratory Syncytial Virus antibody [2F7] (ab43812)](https://www.abcam.cn/ps/products/43/ab43812/Images/ab43812-264031-anti-respiratory-syncytial-virus-antibody-2f7-immunofluorescence.jpg "Immunocytochemistry/ Immunofluorescence - Anti-Respiratory Syncytial Virus antibody [2F7] (ab43812)")
Key features and details
- Mouse monoclonal [2F7] to Respiratory Syncytial Virus
- Suitable for: WB, IHC-Fr, ICC/IF, ELISA
- Reacts with: Respiratory syncytial virus
- Isotype: IgG1
概述
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产品名称
Anti-Respiratory Syncytial Virus抗体[2F7]
参阅全部 Respiratory Syncytial Virus 一抗 -
描述
小鼠单克隆抗体[2F7] to Respiratory Syncytial Virus -
宿主
Mouse -
经测试应用
适用于: WB, IHC-Fr, ICC/IF, ELISAmore details -
种属反应性
与反应: Respiratory syncytial virus -
免疫原
Recombinant FP
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
Constituents: 0.75% Glycine, 1.21% Tris, 2% Sucrose -
Concentration information loading... -
纯度
Protein A purified -
克隆
单克隆 -
克隆编号
2F7 -
同种型
IgG1 -
轻链类型
kappa -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab43812于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/500 - 1/5000. Predicted molecular weight: 48 , 70 kDa.
|
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| IHC-Fr |
1/100 - 1/500.
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| ICC/IF |
1/100 - 1/500.
Immunocytology on infected cells. |
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| ELISA |
1/1000 - 1/2000.
|
| 说明 |
|---|
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WB
1/500 - 1/5000. Predicted molecular weight: 48 , 70 kDa. |
|
IHC-Fr
1/100 - 1/500. |
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ICC/IF
1/100 - 1/500. Immunocytology on infected cells. |
|
ELISA
1/1000 - 1/2000. |
靶标
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相关性
Respiratory syncytial virus (RSV) is a major cause of respiratory illness in young children. RSV infection produces a variety of signs and symptoms involving different areas of the respiratory tract, from the nose to the lungs. RSV is a negative sense, enveloped RNA virus. The virion is variable in shape and size with average diameter of between 120 and 300 nm. The 63 kD RSV fusion protein of the RSS 2 strain (subtype A) directs fusion of viral and cellular membranes, results in viral penetration, and can direct fusion of infected cells with adjoining cells, resulting in the formation of syncytia or multi nucleated giant cells. -
细胞定位
Virion. Host cytoplasm -
数据库链接
- Entrez Gene: 2829063 Respiratory syncytial virus
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别名
- RS virus antibody
- RSV antibody
图片
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Immunocytochemistry/ Immunofluorescence - Anti-Respiratory Syncytial Virus antibody [2F7] (ab43812)Image from Krzyzaniak MA et al., PLoS Pathogens. 2013;9(4):e1003309. Fig 2.; doi: 10.1371/journal.ppat.1003309 Reproduced under the Creative Commons license http://creativecommons.org/licenses/by/4.0/
Immunofluorescent staining of Respiratory Syncytial Virus F protein Bound to HeLa cells using ab43812. Respiratory Syncytial Virus F protein was visualized in green and Respiratory Syncytial N protein in red.
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (16)
ab43812 被引用在 16 文献中.
- Francese R et al. Identification of a βCD-Based Hyper-Branched Negatively Charged Polymer as HSV-2 and RSV Inhibitor. Int J Mol Sci 23:N/A (2022). PubMed: 35955832
- Liu X et al. Human parainfluenza virus type 3 expressing the respiratory syncytial virus pre-fusion F protein modified for virion packaging yields protective intranasal vaccine candidates. PLoS One 15:e0228572 (2020). PubMed: 32045432
- Bialobrzeska W et al. Electrochemical Immunosensors Based on Screen-Printed Gold and Glassy Carbon Electrodes: Comparison of Performance for Respiratory Syncytial Virus Detection. Biosensors (Basel) 10:N/A (2020). PubMed: 33202922
- Pålsson SA et al. Single-Stranded Oligonucleotide-Mediated Inhibition of Respiratory Syncytial Virus Infection. Front Immunol 11:580547 (2020). PubMed: 33363532
- Mehedi M et al. Multicolor Stimulated Emission Depletion (STED) Microscopy to Generate High-resolution Images of Respiratory Syncytial Virus Particles and Infected Cells. Bio Protoc 7:N/A (2017). PubMed: 29057295