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Anti-RELM beta抗体(ab11429)

Submit a review Q&A (2)References (5)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RELM beta antibody (ab11429)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RELM beta antibody (ab11429)

Key features and details

  • Rabbit polyclonal to RELM beta
  • Suitable for: IHC-P
  • Reacts with: Mouse
  • Isotype: IgG

概述

  • 产品名称

    Anti-RELM beta抗体
    参阅全部 RELM beta 一抗

  • 描述

    兔多克隆抗体to RELM beta

  • 宿主

    Rabbit

  • 经测试应用

    适用于: IHC-Pmore details

  • 种属反应性

    与反应: Mouse

  • 免疫原

    Recombinant full length protein corresponding to Mouse RELM beta.

  • 阳性对照

    • Mouse colon.

  • 常规说明

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

性能

应用

The Abpromise guarantee

Abpromise™承诺保证使用ab11429于以下的经测试应用

“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。

应用 Ab评论 说明
IHC-P
1/100.
说明
IHC-P
1/100.

靶标

  • 功能

    Probable hormone.

  • 组织特异性

    Expressed only in the gastrointestinal tract, particularly the colon.

  • 序列相似性

    Belongs to the resistin/FIZZ family.

  • 细胞定位

    Secreted.
  • Information by UniProt

  • 数据库链接

    • 别名

      • C/EBP epsilon regulated myeloid specific secreted cysteine rich protein precursor 2 antibody
      • CCGR antibody
      • Colon and small intestine specific cysteine rich protein antibody
      • Colon and small intestine-specific cysteine-rich protein antibody
      • Colon carcinoma related gene protein antibody
      • Colon carcinoma-related gene protein antibody
      • Cysteine rich secreted A12 alpha like protein 1 antibody
      • Cysteine rich secreted protein A12 alpha like 1 antibody
      • Cysteine rich secreted protein FIZZ2 antibody
      • Cysteine-rich secreted protein A12-alpha-like 1 antibody
      • Cysteine-rich secreted protein FIZZ2 antibody
      • FIZZ1 antibody
      • FIZZ2 antibody
      • Found in inflammatory zone 1 antibody
      • HXCP2 antibody
      • RELM beta antibody
      • RELMb antibody
      • RELMbeta antibody
      • Resistin like beta antibody
      • Resistin like protein beta antibody
      • Resistin-like beta antibody
      • RETNB_HUMAN antibody
      • RETNL2 antibody
      • Retnlb antibody
      • XCP2 antibody
      see all

    图片

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RELM beta antibody (ab11429)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RELM beta antibody (ab11429)

      ab11429 labelling RELM in Mouse colon tissue sections by Immunohistochemistry (formalin/PFA-fixed paraffin-embedded sections).

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RELM beta antibody (ab11429)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RELM beta antibody (ab11429)

      ab11429 labelling RELM in Mouse colon tissue sections by Immunohistochemistry (formalin/PFA-fixed paraffin-embedded sections).

    文献 (5)

    发表研究结果有使用 ab11429？请让我们知道，以便我们可以引用本数据表中的参考文章。

    ab11429 被引用在 5 文献中.

    • Steel N  et al. TGFß-activation by dendritic cells drives Th17 induction and intestinal contractility and augments the expulsion of the parasite Trichinella spiralis in mice. PLoS Pathog 15:e1007657 (2019). PubMed: 30998782
    • Jiang Y  et al. TGF-ß1-induced SMAD2/3/4 activation promotes RELM-ß transcription to modulate the endothelium-mesenchymal transition in human endothelial cells. Int J Biochem Cell Biol 105:52-60 (2018). PubMed: 30120989
    • Scott F  et al. Identification of Flavin-Containing Monooxygenase 5 (FMO5) as a Regulator of Glucose Homeostasis and a Potential Sensor of Gut Bacteria. Drug Metab Dispos 45:982-989 (2017). PubMed: 28646079
    • Busch RA  et al. Bombesin Preserves Goblet Cell Resistin-Like Molecule ß During Parenteral Nutrition but Not Other Goblet Cell Products. JPEN J Parenter Enteral Nutr 40:1042-9 (2016). PubMed: 25934045
    • Akbari M  et al. Direct interaction between XRCC1 and UNG2 facilitates rapid repair of uracil in DNA by XRCC1 complexes. DNA Repair (Amst) 9:785-95 (2010). PubMed: 20466601

    客户评价及客户问答

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    1-2 of 2 Abreviews or Q&A

    Question

    Has this antibody been tested for specificity to RELM beta?

    Read More
    Answer

    Thank you for your phone call yesterday and for your patience while I have been in touch with the lab. Ab11429 has not been tested against other RELM proteins and it is unknown whether it will cross-react with the other forms. This polyclonal antibody was raised against full-length recombinant mouse RELM beta, so there will likely be epitopes all over the protein surface and if there are regions of homology with other RELM proteins there may be crossreactivity. If you are having any problems with the antibody or if you have concerns, please let me know and I will be happy to help you.

    Read More

    Question

    BATCH NUMBER 141719 ORDER NUMBER -- NOT SPECIFIED -- DESCRIPTION OF THE PROBLEM No staining SAMPLE mouse intestine PRIMARY ANTIBODY RELM beta (ab11429) DETECTION METHOD peroxidase DAB staining POSITIVE AND NEGATIVE CONTROLS USED negative control performed positive control not performed ANTIBODY STORAGE CONDITIONS store -20 degree store on ice about 6 hrs before use FIXATION OF SAMPLE Ethanol 75% Acetic acid 25% ANTIGEN RETRIEVAL non PERMEABILIZATION STEP 60 min BLOCKING CONDITIONS 2.5% horse serum SECONDARY ANTIBODY ImmPRESS anti-rabbit Ig HOW MANY TIMES HAVE YOU TRIED THE APPLICATION? 1 HAVE YOU RUN A "NO PRIMARY" CONTROL? Yes DO YOU OBTAIN THE SAME RESULTS EVERY TIME? No

    Read More
    Answer

    Thank you for your enquiry. I am sorry to hear that you have been having problems with this antibody. I have read your technical questionaire and I have a few comments. You are using mouse intestine which is a positive control that we recommend. However, I would appreciate it if you could tell me the dilution factor that you have been applying the antibody at. We recommend the antibody is applied at a dilution of 1:100. Could you also tell me whether the permeabilization agent is triton? I am currently in correspondence with my colleagues in the lab to determine the protocol that was employed for the testing of this antibody by IHC-P. I will forward any information that becomes available.

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