重组Anti-RASSF2抗体[EPR6621] (ab124786)
![Western blot - Anti-RASSF2 antibody [EPR6621] (ab124786)](https://www.abcam.cn/ps/products/124/ab124786/Images/ab124786-138667-anti-rassf2-antibody-epr6621-western-blot.jpg "Western blot - Anti-RASSF2 antibody [EPR6621] (ab124786)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR6621] to RASSF2
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
概述
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产品名称
Anti-RASSF2抗体[EPR6621]
参阅全部 RASSF2 一抗 -
描述
兔单克隆抗体[EPR6621] to RASSF2 -
宿主
Rabbit -
经测试应用
适用于: WBmore details
不适用于: Flow Cyt,ICC/IF,IHC-P or IP -
种属反应性
与反应: Human -
免疫原
Synthetic peptide within Human RASSF2 aa 300-400 (C terminal). The exact sequence is proprietary.
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阳性对照
- Raji, Jurkat and SH-SY5Y cell lysates.
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常规说明
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
解离常数（KD）
KD = 3.80 x 10 -11 M Learn more about KD -
存储溶液
pH: 7.20
Preservative: 0.05% Sodium azide
Constituents: 40% Glycerol (glycerin, glycerine), 9.85% Tris glycine, 50% Tissue culture supernatant -
Concentration information loading... -
纯度
Protein A purified -
克隆
单克隆 -
克隆编号
EPR6621 -
同种型
IgG -
研究领域
相关产品
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Alternative Versions
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab124786于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/1000 - 1/10000. Predicted molecular weight: 37 kDa.
|
| 说明 |
|---|
|
WB
1/1000 - 1/10000. Predicted molecular weight: 37 kDa. |
应用说明
Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
靶标
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功能
Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. -
组织特异性
Widely expressed with highest levels in brain, placenta, peripheral blood and lung. Frequently down-regulated in lung tumor cell lines. -
序列相似性
Contains 1 Ras-associating domain.
Contains 1 SARAH domain. -
细胞定位
Nucleus. - Information by UniProt
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数据库链接
- Entrez Gene: 9770 Human
- Omim: 609492 Human
- SwissProt: P50749 Human
- Unigene: 631504 Human
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别名
- CENP 34 antibody
- Centromere protein 34 antibody
- Ras association (RalGDS/AF 6) domain family 2 antibody
see all
图片
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Western blot - Anti-RASSF2 antibody [EPR6621] (ab124786)All lanes : Anti-RASSF2 antibody [EPR6621] (ab124786) at 1/1000 dilution
Lane 1 : Raji cell lysate
Lane 2 : Jurkat cell lysate
Lane 3 : SH-SY5Y cell lysate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : Standard HRP labelled goat anti-rabbit at 1/2000 dilution
Predicted band size: 37 kDa -
![OI-RD Scanning - Anti-RASSF2 antibody [EPR6621] (ab124786)](https://www.abcam.cn/ps/products/124/ab124786/Images/ab124786-138666-anti-rassf2-antibody-epr6621.jpg)
OI-RD Scanning - Anti-RASSF2 antibody [EPR6621] (ab124786) -
![Anti-RASSF2 antibody [EPR6621] (ab124786)](https://www.abcam.cn/ps/products/124/ab124786/Images/ab124786-3-benefits-of-recombinant-antibodies.png)
Anti-RASSF2 antibody [EPR6621] (ab124786)
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab124786 被引用在 1 文献中.
- Guerrero-Setas D et al. RASSF2 hypermethylation is present and related to shorter survival in squamous cervical cancer. Mod Pathol N/A:N/A (2013). IHC ; Human . PubMed: 23542458