Anti-RAP1/RABGEF1抗体(ab113480)
Key features and details
- Rabbit polyclonal to RAP1/RABGEF1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-RAP1/RABGEF1抗体 -
描述
兔多克隆抗体to RAP1/RABGEF1 -
宿主
Rabbit -
特异性
At least four isoforms of RAP1 are known to exist; ab113480 will recognize all four. ab113480 is predicted to not cross-react with other LRRFIP family members.
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经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide corresponding to Human RAP1/RABGEF1 aa 1-100 (internal sequence).
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阳性对照
- Rat brain tissue lysate
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. -
存储溶液
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: 99.98% PBS -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab113480于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 79 kDa.
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| 说明 |
|---|
|
WB
Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 79 kDa. |
靶标
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功能
Rab effector protein acting as linker between gamma-adaptin, RAB4A or RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates nucleotide exchange on RAB5A. Can act as a ubiquitin ligase. -
序列相似性
Contains 1 A20-type zinc finger.
Contains 1 VPS9 domain. -
翻译后修饰
Monoubiquitinated. -
细胞定位
Cytoplasm. Early endosome. Recycling endosome. - Information by UniProt
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数据库链接
- Entrez Gene: 27342 Human
- Omim: 609700 Human
- SwissProt: Q9UJ41 Human
- Unigene: 530053 Human
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别名
- RAB guanine nucleotide exchange factor (GEF) 1 antibody
- Rab5 GDP/GTP exchange factor antibody
- Rab5ef antibody
see all
图片
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Western blot - Anti-RAP1/RABGEF1 antibody (ab113480)Lane 1 : Anti-RAP1/RABGEF1 antibody (ab113480) at 1 µg/ml
Lane 2 : Anti-RAP1/RABGEF1 antibody (ab113480) at 2 µg/ml
All lanes : Human liver tissue lysate
Predicted band size: 79 kDa
数据表及文件
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SDS download
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Datasheet download
文献 (4)
ab113480 被引用在 4 文献中.
- Wang Y et al. Roles of Rufy3 in experimental subarachnoid hemorrhage-induced early brain injury via accelerating neuronal axon repair and synaptic plasticity. Mol Brain 15:35 (2022). PubMed: 35461284
- Liu X et al. Overexpression of RAPGEF3 enhances the therapeutic effect of dezocine in treatment of neuropathic pain. Genet Mol Biol 44:e20200463 (2021). PubMed: 34807222
- Kan L et al. TMT-based quantitative proteomic analysis of antitumor mechanism of Sporisorium reilianum polysaccharide WM-NP-60 against HCT116 cells. Int J Biol Macromol 165:1755-1764 (2020). PubMed: 33068624
- Kang L et al. RABEX-5 overexpression in gastric cancer is correlated with elevated MMP-9 level. Am J Transl Res 8:2365-74 (2016). PubMed: 27347344