Anti-RAD52抗体(ab18264)
Key features and details
- Rabbit polyclonal to RAD52
- Suitable for: IP, ICC/IF, Electron Microscopy, WB
- Reacts with: Human
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术，可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-RAD52抗体
参阅全部 RAD52 一抗 -
描述
兔多克隆抗体to RAD52 -
宿主
Rabbit -
经测试应用
适用于: IP, ICC/IF, Electron Microscopy, WBmore details -
种属反应性
与反应: Human -
免疫原
Recombinant full length protein (Human).
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
Preservative: 0.02% Sodium azide
Constituent: 99.98% PBS -
Concentration information loading... -
纯度
Whole antiserum -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab18264于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IP |
Use at an assay dependent concentration.
|
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| ICC/IF | (1) |
Use at an assay dependent concentration.
|
| Electron Microscopy |
Use at an assay dependent concentration.
|
|
| WB |
Use at an assay dependent concentration.
|
| 说明 |
|---|
|
IP
Use at an assay dependent concentration. |
|
ICC/IF
Use at an assay dependent concentration. |
|
Electron Microscopy
Use at an assay dependent concentration. |
|
WB
Use at an assay dependent concentration. |
靶标
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功能
Involved in double-stranded break repair. Plays a central role in genetic recombination and DNA repair by promoting the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase. -
序列相似性
Belongs to the RAD52 family. -
翻译后修饰
Phosphorylated upon DNA damage, probably by ATM or ATR. -
细胞定位
Nucleus. - Information by UniProt
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数据库链接
- Entrez Gene: 5893 Human
- Omim: 600392 Human
- SwissProt: P43351 Human
- Unigene: 410355 Human
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别名
- DNA repair protein RAD52 antibody
- DNA repair protein RAD52 antibody
- DNA repair protein RAD52 homolog antibody
see all
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (4)
ab18264 被引用在 4 文献中.
- Tan J et al. An R-loop-initiated CSB-RAD52-POLD3 pathway suppresses ROS-induced telomeric DNA breaks. Nucleic Acids Res 48:1285-1300 (2020). PubMed: 31777915
- Ahn JW et al. SERBP1 affects homologous recombination-mediated DNA repair by regulation of CtIP translation during S phase. Nucleic Acids Res 43:6321-33 (2015). PubMed: 26068472
- Tang KW et al. Rad51 and Rad52 are involved in homologous recombination of replicating herpes simplex virus DNA. PLoS One 9:e111584 (2014). Human . PubMed: 25365323
- Muylaert I & Elias P Contributions of nucleotide excision repair, DNA polymerase eta, and homologous recombination to replication of UV-irradiated herpes simplex virus type 1. J Biol Chem 285:13761-8 (2010). WB ; Human . PubMed: 20215648