Anti-RAD3抗体(ab127891)
Key features and details
- Rabbit polyclonal to RAD3
- Suitable for: WB
- Reacts with: Saccharomyces cerevisiae
- Isotype: IgG
概述
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产品名称
Anti-RAD3抗体 -
描述
兔多克隆抗体to RAD3 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Saccharomyces cerevisiae -
免疫原
Recombinant fragment, corresponding to a region within N terminal amino acids 1-147 of Saccharomyces cerevisiae RAD3 (P06839).
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阳性对照
- Saccharomyces cerevisiae cell lysate.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine) -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab127891于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/500 - 1/3000. Predicted molecular weight: 90 kDa.
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| 说明 |
|---|
|
WB
1/500 - 1/3000. Predicted molecular weight: 90 kDa. |
靶标
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功能
ATP-dependent DNA helicase involved in excision repair of DNA damaged with UV light, bulky adducts, or cross-linking agents. Necessary for excision of pyrimidine dimers. Also unwinds DNA/RNA duplexes. Plays an essential role in the cell viability. Involved in the maintenance of the fidelity of DNA replication. Acts as component of the general transcription and DNA repair factor IIH (TFIIH) core, which is essential for both basal and activated transcription, and is involved in nucleotide excision repair (NER) of damaged DNA. TFIIH has CTD kinase and DNA-dependent ATPase activity, and is essential for polymerase II transcription in vitro. -
序列相似性
Belongs to the helicase family. RAD3/XPD subfamily.
Contains 1 helicase ATP-binding domain. -
细胞定位
Nucleus. - Information by UniProt
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数据库链接
- Entrez Gene: 856918 Saccharomyces cerevisiae
- SwissProt: P06839 Saccharomyces cerevisiae
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别名
- DNA repair helicase RAD3 antibody
- General transcription and DNA repair factor IIH subunit RAD3 antibody
- rad3 antibody
see all
图片
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Western blot - Anti-RAD3 antibody (ab127891)Anti-RAD3 antibody (ab127891) at 1/2000 dilution + Saccharomyces cerevisiae whole cell lysate at 10 µg
Predicted band size: 90 kDa
7.5% SDS Page
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab127891 尚未被引用在任何文献中。