Anti-RAB27B抗体(ab76779)
Key features and details
- Mouse polyclonal to RAB27B
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-RAB27B抗体
参阅全部 RAB27B 一抗 -
描述
小鼠多克隆抗体to RAB27B -
宿主
Mouse -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
Recombinant full length protein within Human RAB27B. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
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阳性对照
- RAB27B transfected 293T cell lysate
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.40
Constituent: 100% PBS -
Concentration information loading... -
纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab76779于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB | (1) |
1/500 - 1/1000. Detects a band of approximately 25 kDa (predicted molecular weight: 25 kDa).
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| 说明 |
|---|
|
WB
1/500 - 1/1000. Detects a band of approximately 25 kDa (predicted molecular weight: 25 kDa). |
靶标
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功能
May be involved in targeting uroplakins to urothelial apical membranes. -
组织特异性
Expressed primarily in testis. -
序列相似性
Belongs to the small GTPase superfamily. Rab family. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 5874 Human
- Omim: 603869 Human
- SwissProt: O00194 Human
- Unigene: 25318 Human
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别名
- C25KG antibody
- Rab27b antibody
- RAB27B member RAS oncogene family antibody
see all
图片
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Western blot - Anti-RAB27B antibody (ab76779)All lanes : Anti-RAB27B antibody (ab76779) at 1/500 dilution
Lane 1 : RAB27B transfected 293T cell lysate
Lane 2 : Non-transfected 293T cell lysate
Lysates/proteins at 25 µg per lane.
Secondary
All lanes : Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/5000 dilution
Developed using the ECL technique.
Predicted band size: 25 kDa
Observed band size: 25 kDa
数据表及文件
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Datasheet download
文献 (5)
ab76779 被引用在 5 文献中.
- Park SS et al. Temsirolimus Enhances Anti-Cancer Immunity by Inducing Autophagy-Mediated Degradation of the Secretion of Small Extracellular Vesicle PD-L1. Cancers (Basel) 14:N/A (2022). PubMed: 36077620
- Zhou H et al. Therapeutic inhibition of GAS6-AS1/YBX1/MYC axis suppresses cell propagation and disease progression of acute myeloid leukemia. J Exp Clin Cancer Res 40:353 (2021). PubMed: 34753494
- Underwood R et al. The GTPase Rab27b regulates the release, autophagic clearance, and toxicity of a-synuclein. J Biol Chem 295:8005-8016 (2020). PubMed: 32350025
- Stephens DC et al. Spatiotemporal organization and protein dynamics involved in regulated exocytosis of MMP-9 in breast cancer cells. J Gen Physiol 151:1386-1403 (2019). PubMed: 31676484
- McGrath JA et al. Germline Mutation in EXPH5 Implicates the Rab27B Effector Protein Slac2-b in Inherited Skin Fragility. Am J Hum Genet 91:1115-21 (2012). PubMed: 23176819
