Anti-PTTG1IP抗体(ab128040)
Key features and details
- Rabbit polyclonal to PTTG1IP
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
概述
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产品名称
Anti-PTTG1IP抗体
参阅全部 PTTG1IP 一抗 -
描述
兔多克隆抗体to PTTG1IP -
宿主
Rabbit -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Mouse, Human
预测可用于: Rat
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免疫原
Synthetic peptide, corresponging to an internal region of Human PTTG1IP.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
存储溶液
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol (glycerin, glycerine), 0.88% Sodium chloride
(without Mg2+, Ca2+) -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab128040于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/500 - 1/1000. Predicted molecular weight: 20 kDa.
|
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| IHC-P |
Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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| 说明 |
|---|
|
WB
1/500 - 1/1000. Predicted molecular weight: 20 kDa. |
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IHC-P
Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
靶标
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功能
May facilitate PTTG1 nuclear translocation. -
组织特异性
Ubiquitous. -
序列相似性
Contains 1 PSI domain. -
细胞定位
Membrane. Cytoplasm. Nucleus. According to PubMed:10781616, it is found in the cytoplasm and the nucleus. - Information by UniProt
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数据库链接
- Entrez Gene: 754 Human
- Entrez Gene: 108705 Mouse
- Entrez Gene: 365548 Rat
- Omim: 603784 Human
- SwissProt: P53801 Human
- SwissProt: Q8R143 Mouse
- SwissProt: Q6P767 Rat
- Unigene: 474010 Human
see all -
别名
- 1810010L20Rik antibody
- AI314311 antibody
- AU018448 antibody
see all
图片
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Western blot - Anti-PTTG1IP antibody (ab128040)All lanes : Anti-PTTG1IP antibody (ab128040) at 1/500 dilution
Lane 1 : RAW264.7 cell extract
Lane 2 : RAW264.7 cell extract with synthesized peptide
Predicted band size: 20 kDa -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PTTG1IP antibody (ab128040)ab128040, at a concentration of 5 µg/ml, staining PTTG1IP in paraffin-embedded Human Prostate, Epithelium tissue by Immunohistochemistry.
数据表及文件
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SDS download
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Datasheet download
文献 (5)
ab128040 被引用在 5 文献中.
- Tan C et al. Cell senescence-associated genes predict the malignant characteristics of glioblastoma. Cancer Cell Int 22:411 (2022). PubMed: 36527013
- Tian X et al. Identification of prognostic biomarkers in papillary renal cell carcinoma and PTTG1 may serve as a biomarker for predicting immunotherapy response. Ann Med 54:211-226 (2022). PubMed: 35037540
- Wang K et al. Synovial Mesenchymal Stem Cell-Derived EV-Packaged miR-31 Downregulates Histone Demethylase KDM2A to Prevent Knee Osteoarthritis. Mol Ther Nucleic Acids 22:1078-1091 (2020). PubMed: 33294294
- Hu ZG et al. MicroRNA-329-mediated PTTG1 downregulation inactivates the MAPK signaling pathway to suppress cell proliferation and tumor growth in cholangiocarcinoma. J Cell Biochem 120:9964-9978 (2019). PubMed: 30582202
- Repo H et al. PTTG1-interacting protein (PTTG1IP/PBF) predicts breast cancer survival. BMC Cancer 17:705 (2017). PubMed: 29078751