Anti-PSME1抗体(ab3333)
Key features and details
- Rabbit polyclonal to PSME1
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术，可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-PSME1抗体
参阅全部 PSME1 一抗 -
描述
兔多克隆抗体to PSME1 -
宿主
Rabbit -
特异性
Detects PSME1 (proteasome activator complex subunit 1). -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Mouse
预测可用于: Cow, Pig, Cynomolgus monkey
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免疫原
Synthetic peptide corresponding to Human PSME1 aa 5-22.
Sequence:RVQPEAQAKVDVFREDLC
(Peptide available asab4949) -
阳性对照
- Rat brain extract.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
Constituents: 0.1% BSA, 99% PBS -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use a concentration of 1 µg/ml. Detects a band of approximately 28 kDa (predicted molecular weight: 29 kDa).
By Western blot, this antibody detects a 28 kDa protein representing PSME1 in rat brain extract. |
| 说明 |
|---|
|
WB
Use a concentration of 1 µg/ml. Detects a band of approximately 28 kDa (predicted molecular weight: 29 kDa). By Western blot, this antibody detects a 28 kDa protein representing PSME1 in rat brain extract. |
靶标
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功能
Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome. -
序列相似性
Belongs to the PA28 family. - Information by UniProt
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数据库链接
- Entrez Gene: 510041 Cow
- Entrez Gene: 102141082 Cynomolgus monkey
- Entrez Gene: 19186 Mouse
- Entrez Gene: 397572 Pig
- SwissProt: Q4U5R3 Cow
- SwissProt: P58238 Cynomolgus monkey
- SwissProt: P97371 Mouse
- SwissProt: Q64L94 Pig
see all -
别名
- 11S regulator complex alpha subunit antibody
- 11S regulator complex subunit alpha antibody
- 29 kD MCP activator subunit antibody
see all
图片
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Western blot - Anti-PSME1 antibody (ab3333)
Western blot detection of PSME1 in Hepa 1 cell lysate using ab3333.
数据表及文件
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Datasheet download
文献 (4)
ab3333 被引用在 4 文献中.
- Hülsemann M et al. TC10 regulates breast cancer invasion and metastasis by controlling membrane type-1 matrix metalloproteinase at invadopodia. Commun Biol 4:1091 (2021). PubMed: 34531530
- Donnelly SK et al. Rac3 regulates breast cancer invasion and metastasis by controlling adhesion and matrix degradation. J Cell Biol 216:4331-4349 (2017). PubMed: 29061650
- Glogauer JE et al. Neutrophils Increase Oral Squamous Cell Carcinoma Invasion through an Invadopodia-Dependent Pathway. Cancer Immunol Res 3:1218-26 (2015). PubMed: 26112922
- Pla A et al. TLR4 mediates the impairment of ubiquitin-proteasome and autophagy-lysosome pathways induced by ethanol treatment in brain. Cell Death Dis 5:e1066 (2014). WB ; Mouse . PubMed: 24556681
