Anti-PRX-1抗体(ab211292)
Key features and details
- Rabbit polyclonal to PRX-1
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-PRX-1抗体
参阅全部 PRX-1 一抗 -
描述
兔多克隆抗体to PRX-1 -
宿主
Rabbit -
特异性
At least two isoforms of PRX-1 are known to exist; ab211292 will detect both isoforms. -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide corresponding to Human PRX-1 (internal sequence). 9 amino acid peptide. NP_008833.1.
Database link: P54821 -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.4
Preservative: 0.02% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
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Related Products
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab211292于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
IHC-P |
Use a concentration of 10 µg/ml.
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说明 |
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IHC-P
Use a concentration of 10 µg/ml. |
靶标
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功能
Acts as a transcriptional regulator of muscle creatine kinase (MCK) and so has a role in the establishment of diverse mesodermal muscle types. The protein binds to an A/T-rich element in the muscle creatine enhancer. -
序列相似性
Belongs to the paired homeobox family.
Contains 1 homeobox DNA-binding domain. -
细胞定位
Nucleus. - Information by UniProt
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数据库链接
- Entrez Gene: 5396 Human
- Omim: 167420 Human
- SwissProt: P54821 Human
- Unigene: 283416 Human
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形式
There are 2 isoforms produced by alternative splicing. -
别名
- AGOTC antibody
- Homeobox protein PHOX1 antibody
- Paired mesoderm homeo box 1 antibody
see all
图片
数据表及文件
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Datasheet download
文献 (10)
ab211292 被引用在 10 文献中.
- Cui H et al. CXCL12/CXCR4-Rac1-mediated migration of osteogenic precursor cells contributes to pathological new bone formation in ankylosing spondylitis. Sci Adv 8:eabl8054 (2022). PubMed: 35385310
- Yang C et al. Single-cell spatiotemporal analysis reveals cell fates and functions of transplanted mesenchymal stromal cells during bone repair. Stem Cell Reports 17:2318-2333 (2022). PubMed: 36150383
- Ratnayake WS et al. Atypical PKCs activate Vimentin to facilitate prostate cancer cell motility and invasion. Cell Adh Migr 15:37-57 (2021). PubMed: 33525953
- Feldmann K et al. Mesenchymal Plasticity Regulated by Prrx1 Drives Aggressive Pancreatic Cancer Biology. Gastroenterology 160:346-361.e24 (2021). PubMed: 33007300
- Wu X & Bao H Tumor suppressive microRNA-485-5p targets PRRX1 in human skin melanoma cells, regulating epithelial-mesenchymal transition and apoptosis. Cell Biol Int 45:1404-1414 (2021). PubMed: 33620119
- Xiong W et al. Low-dose aspirin might alleviate the symptoms of preeclampsia by increasing the expression of antioxidative enzymes. Exp Ther Med 22:1418 (2021). PubMed: 34707700
- Figueroa CA et al. Deletion of a-Synuclein in Prrx1-positive cells causes partial loss of function in the central nervous system (CNS) but does not affect ovariectomy induced bone loss. Bone 137:115428 (2020). PubMed: 32417536
- Cabahug-Zuckerman P et al. Site-Specific Load-Induced Expansion of Sca-1+Prrx1+ and Sca-1-Prrx1+ Cells in Adult Mouse Long Bone Is Attenuated With Age. JBMR Plus 3:e10199 (2019). PubMed: 31667455
- Liu C et al. Mechanical Loading Promotes the Expansion of Primitive Osteoprogenitors and Organizes Matrix and Vascular Morphology in Long Bone Defects. J Bone Miner Res N/A:e3668 (2019). PubMed: 30645780
- Sun X et al. Peroxiredoxin 1 silencing inhibited the growth and promoted apoptosis of pancreatic cancer cells via targeting FOXO3 gene. Cancer Manag Res 10:5019-5026 (2018). PubMed: 30464602