AB211292

Anti-PRX-1抗体

Name: PRX-1抗体 (ab211292)| Abcam中文官网
Brand: Abcam Limited
SKU: AB211292
Price: 4606 CNY
Availability: InStock

Anti-PRX-1 antibody

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(19 Publications)

Rabbit Polyclonal PRX-1 antibody. Suitable for IHC-P and reacts with Human samples. Cited in 19 publications. Immunogen corresponding to Synthetic Peptide within Human PRRX1.

查看别名

PMX1, PRRX1, Paired mesoderm homeobox protein 1, Homeobox protein PHOX1, Paired-related homeobox protein 1, PRX-1

2 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PRX-1 antibody (AB211292)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PRX-1 antibody (AB211292)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human skin tissue labeling PRX-1 with ab211292 at 10μg/ml.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PRX-1 antibody (AB211292)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human testis tissue labeling PRX-1 with ab211292 at 10μg/ml.

关键信息

宿主种属

Rabbit

克隆

Polyclonal

亚型

IgG

不含载体蛋白

反应种属

Human

应用

IHC-P

applications

免疫原

Synthetic Peptide within Human PRRX1. The exact immunogen used to generate this antibody is proprietary information.

P54821

特异性

At least two isoforms of PRX-1 are known to exist; ab211292 will detect both isoforms.

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "10 µg/mL", "IHCP-species-notes": "<p></p>" } } }

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性能和储存信息

形式

Liquid

纯化工艺

Affinity purification Immunogen

存储溶液

pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS

运输条件

Blue Ice

分装信息

Upon delivery aliquot

储存信息

Avoid freeze / thaw cycle

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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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靶点信息

Master transcription factor of stromal fibroblasts for myofibroblastic lineage progression. Orchestrates the functional drift of fibroblasts into myofibroblastic phenotype via TGF-beta signaling by remodeling a super-enhancer landscape. Through this function, plays an essential role in wound healing process (PubMed : 35589735). Acts as a transcriptional regulator of muscle creatine kinase (MCK) and so has a role in the establishment of diverse mesodermal muscle types. The protein binds to an A/T-rich element in the muscle creatine enhancer (By similarity). May play a role in homeostasis and regeneration of bone, white adipose tissue and derm (By similarity).. Isoform 1. Transcriptional activator, when transfected in fibroblastic or myoblastic cell lines. This activity may be masked by the C-terminal OAR domain.. Isoform 2. Transcriptional repressor, when transfected in fibroblastic or myoblastic cell lines.

See full target information PRRX1

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文献 (19)

Recent publications for all applications. Explore the full list and refine your search

Scientific reports 15:35547 PubMed41073566

2025

Total flavonoids of rhizoma drynariae improved the osteogenic and pro-angiogenic capacities of BMSCs to accelerate long bone regeneration.

Applications

Unspecified application

Species

Unspecified reactive species

Hengjun Huang,Silu Li,Huang Zhan,Fenfang Gong,Jian Liu,Zhenya Liu,Hui Li,Chengyu Yang

Protein & cell 16:667-684 PubMed40119681

2025

Single-nucleus transcriptomics decodes the link between aging and lumbar disc herniation.

Applications

Unspecified application

Species

Unspecified reactive species

Min Wang,Zan He,Anqi Wang,Shuhui Sun,Jiaming Li,Feifei Liu,Chunde Li,Chengxian Yang,Jinghui Lei,Yan Yu,Shuai Ma,Si Wang,Weiqi Zhang,Zhengrong Yu,Guang-Hui Liu,Jing Qu

Bioactive materials 48:242-256 PubMed40046012

2025

An axolotl limb regeneration-inspired strategy to enhance alveolar bone regeneration.

Applications

Unspecified application

Species

Unspecified reactive species

Rongpu Liu,Guifang Wang,Li Ma,Guangzheng Yang,Sihan Lin,Ningjia Sun,Jiajia Wang,Huijing Ma,Xinquan Jiang,Wenjie Zhang

Journal of orthopaedic translation 48:11-24 PubMed39170748

2024

Hyperbaric oxygen promotes bone regeneration by activating the mechanosensitive Piezo1 pathway in osteogenic progenitors.

Applications

Unspecified application

Species

Unspecified reactive species

Hang Zhou,Hongzhi Liu,Minmin Lin,Hantang Wang,Jingjing Zhou,Ming Li,Xue Yang,Guibing Fu,Chao Liu

Biomedicines 12: PubMed38927412

2024

M2 Macrophages Guide Periosteal Stromal Cell Recruitment and Initiate Bone Injury Regeneration.

Applications

Unspecified application

Species

Unspecified reactive species

Dazhuang Lu,Yingfei Zhang,Shimin Liang,Yang Li,Jia Qing,Lanxin Gu,Xiuyun Xu,Zeying Wang,Xin Gao,Hao Liu,Xiao Zhang,Yongsheng Zhou,Ping Zhang

Frontiers in oncology 14:1383096 PubMed38846981

2024

Exploiting tertiary lymphoid structures gene signature to evaluate tumor microenvironment infiltration and immunotherapy response in colorectal cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Zhu Xu,Qin Wang,Yiyao Zhang,Xiaolan Li,Mei Wang,Yuhong Zhang,Yaxin Pei,Kezhen Li,Man Yang,Liping Luo,Chuan Wu,Weidong Wang

Journal of gastrointestinal oncology 13:2989-3008 PubMed36636075

2023

PRRX1 promotes colorectal cancer stemness and chemoresistance via the JAK2/STAT3 axis by targeting IL-6.

Applications

Unspecified application

Species

Unspecified reactive species

Longzhu Zhong,Wanlin Tan,Qianqiong Yang,Zhaowei Zou,Rui Zhou,Yongsheng Huang,Zhenghua Qiu,Kehong Zheng,Zonghai Huang

Stem cell reports 17:2318-2333 PubMed36150383

2022

Single-cell spatiotemporal analysis reveals cell fates and functions of transplanted mesenchymal stromal cells during bone repair.

Applications

Unspecified application

Species

Unspecified reactive species

Chengyu Yang,Zeshun Li,Yang Liu,Runpeng Hou,Minmin Lin,Linhao Fu,Decheng Wu,Quanying Liu,Kai Li,Chao Liu

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 36:e22530 PubMed36063128

2022

Controlled mechanical loading improves bone regeneration by regulating type H vessels in a S1Pr1-dependent manner.

Applications

Unspecified application

Species

Unspecified reactive species

Chengyu Yang,Yang Liu,Ziyan Wang,Minmin Lin,Chao Liu

Frontiers in oncology 12:858694 PubMed35530319

2022

RNA Demethylase ALKBH5 Prevents Lung Cancer Progression by Regulating EMT and Stemness Regulating p53.

Applications

Unspecified application

Species

Unspecified reactive species

Xiangli Liu,Ziyi Wang,Qiwei Yang,Xiaohai Hu,Qiang Fu,Xinyu Zhang,Wenya Li

View all publications

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Anti-PRX-1抗体

Anti-PRX-1 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PRX-1 antibody (AB211292)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PRX-1 antibody (AB211292)

关键信息

宿主种属

克隆

亚型

不含载体蛋白

反应种属

应用

免疫原

特异性