Anti-Proteasome 26S S2/PSMD2抗体(ab125914)
Key features and details
- Rabbit polyclonal to Proteasome 26S S2/PSMD2
- Suitable for: WB, ICC/IF
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-Proteasome 26S S2/PSMD2抗体
参阅全部 Proteasome 26S S2/PSMD2 一抗 -
描述
兔多克隆抗体to Proteasome 26S S2/PSMD2 -
宿主
Rabbit -
经测试应用
适用于: WB, ICC/IFmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat, Chicken, Cow, Xenopus laevis, Zebrafish
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免疫原
Recombinant fragment corresponding to Human Proteasome 26S S2/PSMD2 aa 504-746.
Database link: Q13200 -
阳性对照
- 293T, A431 and Raji cell lysates and Human A431 cells.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine) -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab125914于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/500 - 1/3000. Predicted molecular weight: 100 kDa.
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| ICC/IF |
1/100 - 1/500.
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| 说明 |
|---|
|
WB
1/500 - 1/3000. Predicted molecular weight: 100 kDa. |
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ICC/IF
1/100 - 1/500. |
靶标
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功能
Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
Binds to the intracellular domain of tumor necrosis factor type 1 receptor. The binding domain of TRAP1 and TRAP2 resides outside the death domain of TNFR1. -
组织特异性
Found in skeletal muscle, liver, heart, brain, kidney, pancreas, lung and placenta. -
序列相似性
Belongs to the proteasome subunit S2 family.
Contains 7 PC repeats. - Information by UniProt
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数据库链接
- Entrez Gene: 5708 Human
- Entrez Gene: 21762 Mouse
- Entrez Gene: 287984 Rat
- Omim: 606223 Human
- SwissProt: Q13200 Human
- SwissProt: Q8VDM4 Mouse
- SwissProt: Q4FZT9 Rat
- Unigene: 518464 Human
see all -
别名
- 26S proteasome non-ATPase regulatory subunit 2 antibody
- 26S proteasome regulatory subunit RPN1 antibody
- 26S proteasome regulatory subunit S2 antibody
see all
图片
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Immunocytochemistry/ Immunofluorescence - Anti-Proteasome 26S S2/PSMD2 antibody (ab125914)
ab125914, at 1/500, staining Proteasome 26S S2/PSMD2 antibody in Human A431 cells by Immunofluorescence (methanol-fixed).
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Western blot - Anti-Proteasome 26S S2/PSMD2 antibody (ab125914)Anti-Proteasome 26S S2/PSMD2 antibody (ab125914) at 1/500 dilution + A431 whole cell lysate at 30 µg
Predicted band size: 100 kDa
Gel concentration: 5%
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab125914 被引用在 1 文献中.
- Ou Q et al. TcpC inhibits neutrophil extracellular trap formation by enhancing ubiquitination mediated degradation of peptidylarginine deiminase 4. Nat Commun 12:3481 (2021). PubMed: 34108482