Anti-Proteasome 19S S4/PSMC1抗体(ab3317)
Key features and details
- Rabbit polyclonal to Proteasome 19S S4/PSMC1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-Proteasome 19S S4/PSMC1抗体
参阅全部 Proteasome 19S S4/PSMC1 一抗 -
描述
兔多克隆抗体to Proteasome 19S S4/PSMC1 -
宿主
Rabbit -
特异性
Detects proteasome 19S subunit S4. -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
Full length protein corresponding to Proteasome 19S S4/PSMC1. Yeast proteasome 19S subunit S4.
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阳性对照
- WB: HeLa cell lysate.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
Constituents: 0.1% BSA, 99% PBS -
Concentration information loading... -
纯度
IgG fraction -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/1000. Detects a band of approximately 56 kDa (predicted molecular weight: 49 kDa).
This antibody detects a 56 kDa protein representing proteasome 19S subunit S4 in HeLa cell lysate. This antibody detects, to a lesser extent, an ~35 kDa protein which could correspond to subunit degradation product. |
| 说明 |
|---|
|
WB
1/1000. Detects a band of approximately 56 kDa (predicted molecular weight: 49 kDa). This antibody detects a 56 kDa protein representing proteasome 19S subunit S4 in HeLa cell lysate. This antibody detects, to a lesser extent, an ~35 kDa protein which could correspond to subunit degradation product. |
靶标
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功能
The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. -
序列相似性
Belongs to the AAA ATPase family. -
细胞定位
Cytoplasm. Nucleus. - Information by UniProt
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数据库链接
- Entrez Gene: 5700 Human
- Omim: 602706 Human
- SwissProt: P62191 Human
- Unigene: 356654 Human
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别名
- 26S protease regulatory subunit 4 antibody
- 26S proteasome AAA-ATPase subunit RPT2 antibody
- MGC24583 antibody
see all
图片
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Western blot - Anti-Proteasome 19S S4/PSMC1 antibody (ab3317)
Western blot of proteasome 19S subunit S4 on HeLa cell lysate using ab3317.
实验方案
数据表及文件
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Datasheet download
文献 (4)
ab3317 被引用在 4 文献中.
- Adelöf J et al. PA28aß overexpression enhances learning and memory of female mice without inducing 20S proteasome activity. BMC Neurosci 19:70 (2018). PubMed: 30400847
- Zhou X et al. HIV Replication in CD4+ T Lymphocytes in the Presence and Absence of Follicular Dendritic Cells: Inhibition of Replication Mediated by {alpha}-1-Antitrypsin through Altered I{kappa}B{alpha} Ubiquitination. J Immunol 186:3148-55 (2011). WB, IP . PubMed: 21263074
- Rousseau E et al. Misfolding of proteins with a polyglutamine expansion is facilitated by proteasomal chaperones. J Biol Chem 284:1917-29 (2009). WB, ICC/IF ; Human, Rat . PubMed: 18986984
- Sun X et al. Molecular characterization of tumour heterogeneity and malignant mesothelioma cell differentiation by gene profiling. J Pathol 207:91-101 (2005). PubMed: 16007577
